نتایج جستجو برای: s disease pd
تعداد نتایج: 2167246 فیلتر نتایج به سال:
more than 10 million people worldwide are living with parkinson’s disease (pd). the ages of people who have parkinson are variable, usually between 50 and 80 years, the average of them is 55 years old. the symptoms of pd are progressive, and within 10 to 20. it happens when dopaminergic neurons were being degenerate. peripheral and central inflammatory and oxidative stress pathways play a compl...
Background and purpose: Parkinson's disease (PD) is a prevalent movement disorder in elderly with progressive motor complications due to antioxidant defense system deficiency and accumulation of degraded proteins in dopaminergic neurons of midbrain. Ginkgolide is biologically active terpenic lactones as a polyphenol, with potent antioxidant and anti-inflammatory properties. The present study ai...
background: there is no documented demographical study on iranian parkinson's disease (pd) patients, so this study was conducted to identify demographic information about patients with pd in iran, and to explore demographical differences between pd patients in iran and other countries. methods: we reviewed medical records of 1656 patients diagnosed with pd, who referred from all parts of iran t...
تأثیر سه الگوی تمرینی روی قدرت عضلانی موشهای صحرایی مبتلا به پارکینسون القایی با 6-هیدروکسی دوپامین
Background and Aims: Parkinson Disease (PD) as a second neurodegenerative disease has grown in developed and industrial countries due to high life span, and in Iran it is considered an important neurodegenerative disease either. The drug therapy of PD must be paralleled with other treatments because the age of PD occurrence has decreased in recent decades and disturbed active population life st...
statement of problem: periodontal disease (pd) has been linked to adverse cardiovascular events by unknown mechanisms. c-reactive protein (crp) is a prognostic marker for cardiovascular disease, with reported elevated serum levels during pd. purpose: the aim of the present study was to evaluate the association between pd and higher crp levels in the serum of acute myocardial infarction (ami) pa...
Objective Parkinson's Disease (PD) is a neurodegenerative progressive condition with a number of nonmotor symptoms such as depression, anxiety, and stress. These have the most debilitating characteristics and increase the severity and progression of the disease and often reduce functional ability in the sufferers. For this reason, they may, over time, lose their daily living activities skills (...
Background: Autophagy is a mechanism disassembling the damaged organelles from the cell. This study attempted to examine the expression of several autophagy-related genes in Parkinson’s disease (PD) rat model. Methods: The male Wistar rats were divided into three groups as control, sham, and lesion. In the latter group, the PD rat model was induced by the injection of 6-hydroxydopamine in...
Objective(s): The present study was conducted to examine the effect of sleep deprivation (SD) on the anti-apoptotic pathways in Parkinsonian rats. Materials and Methods: Male Wistar rats (n = 40) were assigned to four groups (10 animals each): sham surgery (Sham), 6-hydroxydopamine (6-OHDA)-lesioned (OH), 6-OHDA-lesioned plus grid control (OH+GC), 6-OHDA-lesioned plus SD (OH+SD). Parkinson’s di...
1.1 Clinical characteristics of Parkinson’s disease Parkinson’s disease (PD) is an old-age neurodegenerative disease with a small but significant genetic risk. The prevalence of PD is of 0.3% in the whole population, affecting more than 1% of the humans over 60 years of age (de Lau & Breteler, 2006). Parkinson ́s disease is characterized by the progressive loss of dopamine due to degeneration of...
introduction: oxidative stress seems to play a critical role in the degeneration of dopaminergic neurons in parkinson’s disease (pd). antioxidant compounds can deactivate and scavenge free radical. olive leaves are considered as a useful source of phenolic compounds. therefore, this study was designed to investigate the effects of methanolic olive leaf extract (ole) on neurobehavioral activity ...
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