BACKGROUND Hypothesizing that statins may be useful as adjuvant treatment for renal anemia, we examined the association between statin prescription (Rx) and erythropoiesis-stimulating agent (ESA) hyporesponsiveness in Japanese hemodialysis (HD) patients prescribed ESAs. METHODS We examined 3,602 patients in 60 HD facilities dialyzed 3 times/week for ≥4 months from the Japan Dialysis Outcomes ...

Real-time anomaly detection has received wide attention in remote sensing image processing because many moving targets must be detected on a timely basis. A widely-used anomaly detection algorithm is the Reed-Xiaoli (RX) algorithm that was proposed by Reed and Yu. The kernel RX algorithm proposed by Kwon and Nasrabadi is a nonlinear version of the RX algorithm and outperforms the RX algorithm i...

Rx in potato encodes a protein with a nucleotide binding site (NBS) and leucine-rich repeats (LRR) that confers resistance against Potato virus X. The NBS and LRR domains in Rx are present in many disease resistance proteins in plants and in regulators of apoptosis in animals. To investigate structure-function relationships of NBS-LRR proteins we exploited the potential of Rx to mediate a cell ...

A disulfide-linked nitroxide side chain (R1) is the most widely used spin label for determining protein topology, mapping structural changes, and characterizing nanosecond backbone motions by site-directed spin labeling. Although the internal motion of R1 and the number of preferred rotamers are limited, translating interspin distance measurements and spatial orientation information into struct...

PURPOSE To quantify the relationship between velocity and pressure gradient in a distal protection filter (DPF) and to determine the feasibility of modeling a DPF as a permeable surface using computational fluid dynamics (CFD). METHODS Four DPFs (Spider RX, FilterWire EZ, RX Accunet, and Emboshield) were deployed in a single tube representing the internal carotid artery (ICA) in an in vitro f...

We present XMM-Newton data of three strongly magnetic cataclysmic variables (polars) EV UMa, RX J1002-19 and RX J1007-20. These include the polar with the shortest orbital period (EV UMa) and the polar with one of the highest magnetic field strengths (RX J1007–20). They exhibit a range of X-ray spectral characteristics which are consistent with their known magnetic field strength. We find that ...

During the last decades, the share of population using prescription (Rx) medicines has considerably increased. With the wider introduction of self-medication and the use of over-the-counter (OTC) medicines, there is a real threat for drug-drug interactions between Rx and OTC medicines neither identified nor overseen by healthcare specialists. The objectives of this survey were to ascertain how ...

We performed time-series photometry of the PG1159-type star HE 1429−1209, which was recently discovered in the ESO SPY survey. We show that the star is a low-amplitude (≈0.05 mag) non-radial g-mode pulsator with a period of 919 s. HE 1429−1209 is among the hottest known post-AGB stars (T eff =160 000 K) and, together with the known pulsator RX J2117.1+3412, it defines empirically the blue edge ...