231 Received March 23, 2012; revision accepted for publication June 21, 2012. doi: 10.1620/tjem.227.231 Correspondence: Shingo Noguchi, M.D., Department of Respiratory Medicine, University of Occupational and Environmental Health, Iseigaoka, Yahatanishiku, Kitakyushu city, Fukuoka 807-8555, Japan. e-mail: [email protected] Intrathoracic Rosai-Dorfman Disease with Spontaneous Remission: A ...

Rosai-Dorfman disease (RDD) is a rare benign proliferative disorder of histiocytes in the lymph nodes with or without extranodal involvement. RDD limited to the skin without nodal involvement, known as cutaneous Rosai-Dorfman disease, is very rare. We describe a 34-year-old female with RDD of the skin over the chest. A large nodule with satellite lesions was excised for histopathological examin...

Rosai-Dorfman disease is a rare, benign presenting with extensive lymphadenopathy. In this case, an 81-year-old gentleman previous pulmonary tuberculosis, presented painless cervical lymphadenopathy associated generalized weakness, loss of appetite, and cough.

Successful Treatment of Rosai-DorfmanDisease With Low-DoseOral Thalidomide Rosai–Dorfman disease (RDD) is a rare idiopathic histiocytic proliferative disorder.1 The skin is the most frequently involved extranodal organ. Nevertheless, primary cutaneous manifestation of RDD (CRDD) without systemic involvement is rare.2 We present herein a case of CRDD showing excellent remission after low-dose or...

Rosai-Dorfman disease is a rare benign histiocytic disorder that arises predominantly in lymph nodes with fever and malaise, but can affect various organs, with or without lymphadenopathy. Solitary extranodal skeletal lesions are extremely rare. Herein, we describe a case of isolated disease of thoracic spine, with vertebral body fracture. A 14-year-old girl presented with cervical back pain fo...

BACKGROUND Rosai-Dorfman is a rare disease that usually occurs in young adults. It is characterized with massive painless cervical lymphadenopathy and histiocyte proliferation. Isolated intracranial involvement is extremely rare. Our aim is to present a new rare case of extranodal Rosai-Dorfman disease that involved the right optic nerve in a 4-year-old boy. CASE DESCRIPTION A 4-year-old boy ...