We recently identified a novel human protein kinase, p160 ROCK, as a putative downstream target of the small GTPase Rho. Using the human ROCK cDNA as a probe, we isolated cDNA of two distinct, highly related sequences from mouse libraries. One encoded a mouse counterpart of human ROCK (ROCK-I), and the other encoded a novel ROCK-related kinase (ROCK-II). Like ROCK/ROCK-I, ROCK-II also bound to ...

Drilling into a rock massif is energetically extremely consumptive process. Hence the optimization of drilling regime with objective of energy consumption minimization, is very important. Proposed article discusses partial problem of this problem. During the drilling process it is useful to know the drilled rock type, whereas to particular drilled rock needs convenient drilling regime, which is...

identification of homogenous watershed sub basins allows generalization of environmental study results. for this purpose, first available data for 27 selected watersheds in north alborz regarding 21 variables including physiographic and climatic characteristics was gathered. the most important factors impacting upon soil erosion and sediment yield were equivalent rectangular length, mean annual...

A landslide hazard zonation is a division of the land surface into areas, and the relative ranking of these areas according to degrees of actual or potential hazard from landslides on slopes. Zonation from scientific research does not generally imply legal restrictions, but can be useful to those people who are charged with the land management, by providing them with information that is indispe...

protein serine/threonine kinase (ROCK), is one of the central regulatory molecules for cytoskeleton control and cell adhesion process. ROCK also involves in other cell functions such as apoptosis and tumor invasiveness. Rho kinase is thought to play an important role in a variety of cellar functions such as stress fiber formation, focal adhesion formation, cell aggregation, cell morphology, cyt...

In this work, the effect of rock bolt angle on the shear behavior of Rock Bridges is investigated using the particle flow code in two dimensions (PFC2D) for three different Rock Bridge lengths. Firstly, the calibration of PF2D is performed to reproduce the gypsum sample. Then the numerical models with the dimensions of 100 mm * 100 mm are prepared. The Rock Bridge is created in the middle of th...

No prior research has documented the different types of rock coatings in Yosemite Valley, despite the evident black streaks down Yosemite Falls, the light granitic rock exposed by recent rock falls contrasting with dark rock coatings, and the millions of visitors who have photographed the coated rocks of Yosemite. This paper identifies the types of rock coatings found on Half Dome, in Yosemite ...