This paper will focus on understanding the role and action of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in the molecular and biochemical pathways responsible for the regulation of the survival of hair cells and spiral ganglion neurons in the auditory portion of the inner ear. The pivotal role of ROS/RNS in ototoxicity makes them potentially valuable candidates for effect...

Pure preparations of envelope glycoproteins E(rns) and E2 of classical swine fever virus (CSFV) synthesized in insect cells were used to study infection of porcine and bovine cells with the pestiviruses CSFV and bovine viral diarrhoea virus (BVDV). Almost 100% inhibition of infection of porcine kidney cells with CSFV was produced by 100 microg/ml E(rns). After removal of the virus no E(rns) was...

BACKGROUND To evaluate the risk of cancer among Taiwanese female registered nurses (RNs) using a nationwide population-based dataset. METHODS We recruited female RNs without antecedent cancer from the Taiwan National Health Insurance Research database during 2000-2010. Standardized incidence ratios (SIRs) of cancer were calculated. We also compared rates of Papanicolaou (Pap) smear use betwee...

Background: Responsive Neurostimulation (RNS) has proven efficacy in the treatment of medically resistant epilepsy as an intracranial system that detects, records and treats seizures automatically. No information exists pertaining to artifact characteristics RNS findings scalp EEG. Methods: A 30 year-old female was diagnosed, using electroencephalography (iEEG), with refractory bi-insular epile...

Scaling is one of the complex operations in Residue Number System (RNS). This operation necessary for RNS-based implementations deep neural networks (DNNs) to prevent overflow. However, state-of-the-art RNS scalers special moduli sets consider 2k modulo as scaling factor, which results a high-precision output with high area and delay. Therefore, low-precision based on multi-moduli factors shoul...

PURPOSE This work was intended to test the classification of Acanthamoeba into genotypes based on nuclear ribosomal RNA gene (18S rDNA, Rns) sequences. Nearly all Acanthamoeba keratitis (AK) isolates are genotype RnsT4. This marked phylogenetic localization is presumably either due to an innate potential for pathogenicity or to a peculiarity of the gene sequences used. To differentiate between ...

Introduction Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generated during normal physiological processes are highly reactive with cellular lipids, DNA, and proteins. Superoxide and nitric oxide are the primary ROS and RNS, respectively, produced in cells, and both species react with other molecules and each other to form a diverse array of additional ROS and RNS (e.g., hyd...

Background: Conflict management among RNs is important when considering the well-being of nurses and the ongoing challenges caused by the shortage of nurses. Objective: The aim of this study was to explore registered nurses’ (RN) perceptions of conflict management in RN-RN collaborations and the relationship between RNs’ backgrounds and conflict management. Methodology: Data were collected from...

Recombination nodules (RNs) are closely correlated with crossing over, and, because they are observed by electron microscopy of synaptonemal complexes (SCs) in extended pachytene chromosomes, RNs provide the highest-resolution cytological marker currently available for defining the frequency and distribution of crossovers along the length of chromosomes. Using the maize inbred line KYS, we prep...

Chronic generation of reactive nitrogen species (RNS) can cause DNA damage and may also directly modify DNA repair proteins. RNS-modified DNA is repaired predominantly by the base excision repair (BER) pathway, which includes the alkyladenine DNA glycosylase (AAG). The AAG active site contains several tyrosines and cysteines that are potential sites for modification by RNS. In vitro, we demonst...