Distal myopathy with rimmed vacuoles (DMRV) is an autosomal recessive or sporadic early adult-onset myopathy caused by mutations in the UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase (GNE) gene. Characteristic pathologic features of DMRV are rimmed vacuoles on muscle biopsy and tubulofilamentous inclusion in ultrastructural study. Presence of inflammation in DMRV is unusual....

We present our diagnosis of the role massive stars play in the formation of lowand intermediate-mass stars in OB associations. In the bright-rimmed and comet-shaped clouds in both the OriOB1 and LacOB1 associations, there is compelling evidence of lowand intermediate-mass star formation dominated by the triggering process by the massive stars in the regions. The expanding ionization fronts from...

Introduction: QUE 94201 (QUE) is a basaltic shergottite containing subequal amounts of pyroxene and plagioclase, the latter having been converted to maskelynite by shock (Fig. 1) [e.g., 1-3]. Pyroxene occurs as elongate subhedral to euhedral grains up to several mm in length. It has extensive and complex zoning (Fig 1). Typical grains have Mg-rich pigeonite cores mantled by Mg-rich augite, whic...

BACKGROUND The autophagic vacuolar myopathies (AVM) are a group of inherited myopathies defined by the presence of autophagic vacuoles in pathological muscle specimens. AVM can be categorized into three groups: acid maltase deficiency, myopathies characterized by autophagic vacuoles with unique sarcolemmal features, and rimmed vacuolar myopathies (RVM). While the pathogeneses of these condition...