We evaluated the distribution of ABO and Rhesus (Rh) D blood groups in the population of Poonch district in Azad Jammu and Kashmir. The blood group phenotypes were detected by the classic slide method. The ABO blood group system in the total sample showed the same trend of prevalence as for the general Indian subcontinent (B > or = O > A > AB). The same trend was found among males, but among fe...

BACKGROUND & OBJECTIVES There is paucity of information on the association between Plasmodium falciparum malaria and some human genetic markers in the Niger Delta region of Nigeria. Hence, a study was undertaken in children to assess the current level of subclinical malaria due to P. falciparum. METHODS Blood groups ABO and Rhesus factor, haemoglobin electrophoretic pattern, G-6-PD deficiency...

Background Few studies have documented the blood group antigens in the population of eastern India. Frequencies of some common alleles and haplotypes were unknown. We describe phenotype, allele, and haplotype frequencies in the state of West Bengal, India. Methods We tested 1,528 blood donors at the Medical College Hospital, Kolkata. The common antigens of the ABO, Rhesus, and Kell blood grou...

BACKGROUND Neonatal jaundice that occurs in ABO or Rhesus issoimunisation has been recognized as one of the major risk factors for development of severe hyperbilirubinemia and bilirubin neurotoxicity. AIM Aim of our study was to investigate clinical and laboratory parameters associated with hemolytic jaundice due to Rh and ABO incompatibility and compare results with the group of unspecific j...

DISCOVERY OF THE RHESUS BLOOD GROUP For many years, doctors had realised that there was a heterogeneous group of newborn babies who developed jaundice, anaemia or both, which were variants of a single underlying disorder, characterised by haemolysis and erythroblastosis. In 1940, Landsteiner and Wiener ' published a paper of less than 20 lines in which they described the discovery of the Rhesus...

Transfusion of one unit or more of Rh-positive red blood cells normally causes circulating anti-D antibody to appear 2-6 months later in 80-95% of Rh- persons. We asked whether transplant immunosuppression with cyclosporine and corticosteroids affects Rh immunization. Nineteen Rh- liver, heart, and heart-lung transplant recipients received 3-153 (median: 10) units of Rh+ RBCs at surgery and wer...

Abstract The aim of this study was to explore temporal and spatial variability the frequency ABO Rhesus blood group phenotypes in Polish donors from Lower Silesia between 1946 1990. Data on 158,134 individuals (113,714 men 44,420 women) were obtained two databases containing information about Silesia. rate direction changes groups evaluated with regression analysis Pearson’s correlation coeffic...

Following the discovery of the Rhesus factor by Landsteiner and Wiener (1940) and the demonstration by Levine, Burnham, Katzin, and Vogel (1941) that haemolytic disease of the newborn generally is the result of mother-child Rh incompatibility several reports of erythroblastosis foetalis attributable to sensitization of the mother by the A or B foetal antigens have been published, notably those ...

To determine which Rh-polypeptide genes are related to which Rh (rhesus) antigens, genomic DNAs prepared from donors of ten kinds of different Rh phenotypes were analysed by Southern hybridization method using two probes for the 5' moiety and 3' moiety of an Rh-polypeptide cDNA. A polymorphism for the Rh blood-group system was observed with BamHI, HindIII, PstI and EcoRI restriction endonucleas...