Primary neoplasms of the patella account for less than 1% of all primary bone tumors of the lower extremity, the most frequent of them being the giant cell tumor of bone, the chondroblastoma, and the aneurysmal bone cyst. Herein, we report the case of a 29-year-old woman with an active giant cell tumor of the patella (GCTP) with its clinical and radiological features and a brief review of the l...

The association between actinic granuloma and giant cell arteritis (temporal arteritis) has been claimed by some authors. There is a hypothesis that actinic radiation has the principal role in the etiology of both diseases in a similar way. Here, we report a case of actinic granuloma that had characteristic pathologic features of giant cell arteritis in histopathologic examination without clini...

Objective(s):miR-125b has been identified as a tumor suppressor in many tumors, but its role in giant cell tumor (GCT) of bone remains poorly understood. The current study aimed to investigate the potential role and mechanism of miR-125b in GCT. Materials and Methods:Expression levels of miR-125b in GCT tissues were determined using RT-PCR. The cell proliferation was surveyed by direct cell coun...

Case Description and Clinical Findings- A seven-year-old male German shepherd dog was referred to Small Animal Clinic with severe lameness (non-weight-bearing) and considerable localized proximal right humerus swelling. Radiographic study revealed severe soft tissue swelling and pathologic fracture of proximal right humerus. Immediately, the right forelimb was removed surgically and once sample...

The giant cell tumor of the tendon sheath is regarded as one of the most common neoplasms of the hand. This tumor usually manifests itself as a localized, solitary, painless and palpable subcutaneous nodule on the palmar aspect of a digit. A multifocal origin of the tumor has rarely been reported in the literature before. In this article we present a case of a giant cell tumor of the tendon she...

Introduction: Central giant cell granuloma is a benign lesion but sometimes has aggressive proliferation composed of multinucleated giant cells in a background of spindle and ovoid mesenchymal cells. Multifocal central giant cell granuloma of jaws is very rare and usually associated with hyperparathyroidism and some syndromes. We described an un-usual case of a 22-year-old man with idi-opathic ...

background and aims. the correlation between morphology of giant cells in peripheral granulomas of the jaws and the aggressive behavior of the lesion is unknown. this study investigated the correlation between the histopathologic features with demographic, gross and radiographic findings in giant cell granulomas. materials and methods. in this analytical study, data from 23 cases of central gia...