Faithful genome duplication and inheritance require the complete resolution of all intertwines within the parental DNA duplex. This is achieved by topoisomerase action ahead of the replication fork or by fork rotation and subsequent resolution of the DNA precatenation formed. Although fork rotation predominates at replication termination, in vitro studies have suggested that it also occurs freq...

In this paper, a new approach is proposed to recover the shape for the restricted observation with the limited rotation angle. This is achieved by combining Shape-from-silhouette and the Hopfield neural network based optimization technique. Under the condition that the number of the observed images is restricted with the limited rotation angle, the original Shape-from-silhouette gives poor resu...