Response modification factor (R-factor) is one of the seismic design parameters to consider nonlinear performance of building structures during strong earthquake. Relying on this, many seismic design codes led to reduce earthquake loads imposed to the structure. The present paper tries to evaluate the R-factors of conventional concentric braced frames (CBFs) and special moment frames (MRFs) in ...

Rck2, a yeast Ser/Thr protein kinase homologous to mammalian calmodulin kinases, requires phosphorylation for activation. We provide evidence that in budding yeast, this step can be executed by the osmostress-activated mitogen-activated protein kinase Hog1. Rck2 phosphorylation was transiently increased during osmostress or in mutants with a hyperactive high osmolarity glycerol (HOG) pathway. T...

the management of carotid artery stenosis reduces the risk of stroke and its related deaths.   management options include risk factor modification and medical therapy, carotid endarterectomy (cea), and carotid artery stenting (cas). although several randomized controlled trials (rcts), mostly conducted in late-1980s and mid-1990s, have proved cea to be effective in the prevention of ipsilateral...

reaching an electricity system which is both economically efficient and environmentally friendly is motivating countries to design and execute different types of tou demand response programs. but there are certain deficiencies which prevent these programs to effectively modify the load shape. smart grid as a means could help the electricity system to reach the highest demand side management ...

A multifactorial approach to the aetiology of oesophageal cancer was made on the basis of a case-control study in Saitama prefecture, Japan. The joint risks of two factors were calculated directly from joint distributions, following a dichotomous exposure model. Three models of factor combinations were taken into account: two risk enhancing factors, two risk reducing factors, and risk enhancing...

current mainstay of treatment for human immunodeficiency virus (hiv)-infected patients is highly active antiretroviral therapy (haart) but little is known about the long-term clinical outcome for hiv-infected patients who have received haart. determining factors associated with longterm survival in the course of treatment may allow modification to be made for patients who are at a greater risk ...