Background: Infections caused by carbapenem-resistant gram-negative bacteria are treated with colonistin as a last resort. However, the increased resistance in recent years is significant for treating multiple drug-resistant infections. Objectives: This study aimed to determine genes mobile colistin (mcr)-1 and mcr-2 colistin-resistant isolates, understand mechanism, help treatment. Methods: Is...

background :   imipenem-resistant gram negative bacteria, resulting from metallo-beta-lactamase (mbls)-producing strains have been reported to be among the important causes of nosocomial infections and of serious therapeutic problem worldwide. because of their broad range, potent carbapenemase activity and resistance to inhibitors, these enzymes can confer resistance to almost all beta-lactams....

  Background and Objective: Metallo-beta-lactamase (MBL)-mediated resistance is an emerging threat in hospital isolates of Pseudomonas aeruginosa. There is not enough information from Iran regarding the prevalence and the screening methods for such enzymes. The present study was undertaken to detect Metallo betalactamase in strains of P. aeruginosa isolated from burned patien...

  Tuberculosis is a serious global public health problem and its high prevalence is stron gly associated with the enhancement of drug resistance. In this study we demonstrate a multiplex allele-specific polymerase chain reaction (MAS)-PCR assay to simultaneously detect mutations in the first and third bases of the embB gene codon 306 ATG in ethambutol (EMB) resistant isolates of Mycobacterium t...

Thirty-one A. baumannii isolates were obtained from Shar and Burn hospitals in Sulaimani City, KRG-Iraq. Bacterial identification was confirmed by detecting both 16S rRNA blaOXA-51 genes. The detection of carbapenem resistant carried out using Kirby- Bauer, RAPDEC Carba NP combined disc assays. A high rate drug resistance observed, as 74.2% the multidrug-resistant (MDR) 38.7% extensively drug-r...

Abstract Background Chlorhexidine is a widely used disinfectant in clinical settings and broad-spectrum antimicrobial agent effective against aerobic anaerobic bacteria. However, resistant or non-susceptible bacteria, including antibiotic-resistant Acinetobacter baumannii, have been found. This study aimed to develop new technique prevent control A. baumannii infection the hospital setting. Met...

the emergence of multi-drug resistant strains of pseudomonas aeruginosa has complicated treatment decision and may lead to treatment failures. in this study, we describe the trends of drug-resistant p. aeruginosa isolated in blood cultures from patients detected in a tertiary teaching hospital and evaluated the prevalence of resistance to amikacin, ampicillin, carbeni- cillin, cefixime, cefotax...

Background: Pseudomonas aeruginosa, as an etiological agent, has a prominent infection role in serious burned patients. Burned patients usually treated with antiseptic ointments such as silver sulfadiazine (SSD). This study evaluated the effectiveness of 1% SSD and different concentrations of silver nitrate solution (SNS) on resistant isolates of P. aeruginosa. Methods: Three groups of P. aerug...

conclusions the cefoxitin disk diffusion method showed the best results when compared to oxacillin disk, similar to results from detecting the meca gene in pcr as a golden test. studies on mrsa that carry the luk-pv gene should continue to provide significant insight into the prevalence and epidemiology of these important resistant pathogens. also, the rate of pvl gene-producing isolates showed...