Immersed, isolated turtle ventricles were allowed to beat when filling only by suction. Obstruction of ejection at various volumes showed an inverse relationship between residual volume and volume aspirated. Diastolie aspiration occurred even with residual volumes of at least 0.55 ml. Ventricles, filling by suction only, maintained continuous output of up to 3 ml./min. working against pressures...

Bin-Amphiphysin-Rvs (BAR) domain proteins are central regulators of many cellular processes involving membrane dynamics. BAR domains sculpt phosphoinositide-rich membranes to generate membrane protrusions or invaginations. Here, we report that, in addition to regulating membrane geometry, BAR domains can generate extremely stable lipid microdomains by "freezing" phosphoinositide dynamics. This ...

Symmetry restrictions due to fluidity require the strain energy in the Helfrich theory of lipid membranes to be locally isotropic in nature. Although this framework is suitable for modeling the interaction of membranes with proteins that generate spherical curvature such as clathrin, there are other important membrane-bending proteins such as BIN-amphiphysin-Rvs proteins that form a cylindrical...

In the context buffer models fed by independent on-off fluid sources, we explore conditions under which “determinism minimizes the stationary backlog.” These comparison results are couched in terms of the convex ordering for distributions. We show that increased variability in the on-duration rv results in greater variability of the corresponding backlog. While it appears that in general increa...

Biological membranes have a central role in mediating the organization of membrane-curving proteins, a dynamic process that has proven to be challenging to probe experimentally. Using atomic force microscopy, we capture the hierarchically organized assemblies of Bin/amphiphysin/Rvs (BAR) proteins on supported lipid membranes. Their structure reveals distinct long linear aggregates of proteins, ...

The purpose of the project was to evaluate an underwater weighing (UWW) and residual lung volume (RV) familiarization program developed for adults with Prader-Willi syndrome (PWS). UWW was conducted on 15 adults (10 men, 5 women) with PWS following a UWW familiarization program. Repeated measures ANOVA revealed no difference in percent body fat derived from UWW over the four sessions, F(3, 27) ...

OBJECTIVE To investigate pulmonary function, working capacity and isokinetic muscle strength in subjects with Marfan syndrome. MATERIALS AND METHODS Seventeen subjects, mean age 23 years, performed spirometry, maximal ergometer cycle tests and knee extension and flexion isokinetic torque tests. RESULTS The subjects with Marfan syndrome had increased total and residual lung volume values com...

Fundamental to many applications in financial engineering is the normal (Gaussian) distribution. It is the building block for simulating such basic stochastic processes as Brownian motion and geometric Brownian motion. In this section, we will go over algorithms for generating univariate normal rvs and learn how to use such algorithms for constructing sample paths of Brownian motion and geometr...

APGAR: Activity Pulse Grimace Appearance Respiration; PImax: Maximal Inspiratory Pressure; PEmax: Maximal Expiratory Pressure; DLCO: Diffusion Capacity; β-HCG: Bbeta Human Chorionic Gonadotropin; BMI: Body Mass Index; FVC: Forced Vital Capacity; FEV1: Forced Expiratory Flow at One Second; FEF25-75: Forced Expiratory Flow 25-75; RV: Residual Volume; TLC: Total Lung Capacity; DLCO/VA: Diffusion C...

Thirty eight assessments of postmicturition residual volume were undertaken in 34 babies of various gestational and postnatal ages using abdominal ultrasonography. Twenty one (54%) babies had no detectable residual bladder volume. In all cases manual expression of the bladder failed to eliminate the residual volume. The formula widely used in the estimation of fetal bladder size and urine outpu...