نتایج جستجو برای: reservoir host
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By definition, zoonotic pathogens are not strict host-species specialists in that they infect humans and at least one nonhuman reservoir species. The majority of zoonotic pathogens infect and are amplified by multiple vertebrate species in nature, each of which has a quantitatively different impact on the distribution and abundance of the pathogen and thus on disease risk. Unfortunately, when n...
Eradication of the latent HIV reservoir remains a major barrier to curing AIDS. However, the mechanisms that direct viral persistence in the host are not well understood. Studying a model system of postintegration latency, we found that viral integration into the actively transcribed host genes led to transcriptional interference (TI) caused by the elongating RNA polymerase II (RNAPII) transcri...
Rodent-borne hantaviruses can cause two human diseases with many pathological similarities: hantavirus cardiopulmonary syndrome (HCPS) in the western hemisphere and hemorrhagic fever with renal syndrome in the eastern hemisphere. Each virus is hosted by specific reservoir species without conspicuous disease. HCPS-causing hantaviruses require animal biosafety level-4 (ABSL-4) containment, which ...
Zoonoses within wild reservoir host populations often occur focally obeying Pavlovskii's rules of "natural nidality". What appears to be a clear example is Bolivian hemorrhagic fever (BHF), a disease endemic to northeastern Bolivia. The etiological agent is Machupo virus (MACV, Arenaviridae). The vertebrate reservoir, identified 30 years ago, was Calomys callosus a wild rodent common to open bi...
background: an epidemiological study was carried out on the vector(s) and reservoir(s) of cutaneous leishmaniasis in rural areas of kalaleh district, golestan province during 2006 - 2007. methods: totally 4900 sand flies were collected using sticky papers and were subjected to molecular methods for detection of leishmanial parasite. results: phlebotomus papatasi was the common species in outdo...
Downing, B.D., B.A. Bergamaschi, D.G. Evans and E. Boss. 2008. Estimating source-specific contributions of DOC into a drinking-water reservoir using optical profiling. Lake Reserv. Manage. 24:381–391. Understanding the sources of dissolved organic carbon (DOC) in drinking-water reservoirs is an important management issue because DOC may form disinfection by-products, interfere with disinfection...
We present the molecular identification of Apodemus agrarius (striped field mouse) as reservoir host of the Dobrava-Belgrade virus (DOBV) lineage DOBV-Aa in 3 federal states of Germany. Phylogenetic analyses provided evidence for multiple spillover of DOBV-Aa to A. flavicollis, a crucial prerequisite for host switch and genetic reassortment.
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