نتایج جستجو برای: renin angiotensin system

تعداد نتایج: 2274298  

Journal: :Circulation research 1974
J O Davis R H Freeman J A Johnson W S Spielman

• The role of the renin-angiotensin system in the control of arterial blood pressure and aldosterone secretion has been studied extensively in homeostasis, hypertensive disease, and edematous states. For many years it has been realized that the availability of effective blocking agents for renin or for angiotensin II might help greatly in the study of this system and might have important value ...

Journal: :Hypertension 1986
V J Dzau

THE circulating renin-angiotensin system plays an important role in blood pressure regulation as well as in fluid and electrolyte balance. Its contribution to cardiovascular homeostasis has been well documented in studies that employ pharmacological or immunological inhibitors." Blockade of the renin-angiotensin system using peptide inhibitors or specific antibodies to renin, angiotensin conver...

2014
Peng Shi Justin L. Grobe Fiona A. Desland Guannan Zhou Xiao Z. Shen Zhiying Shan Meng Liu Mohan K. Raizada Colin Sumners Michelle L. Block

Neuroinflammation has been implicated in hypertension, and microglia have been proposed to play an important role in the progression of this disease. Here, we have studied whether microglia are activated within cardiovascular regulatory area(s) of the brain during hypertension, especially in high blood pressure that is associated with chronic activation of the renin-angiotensin-system. In addit...

Journal: :iranian journal of immunology 0
keyvan amirshahrokhi department of pharmacology, school of medicine, tehran university of medical sciences, tehran, iran mahmoud ghazi-khansari department of pharmacology, school of medicine, tehran university of medical sciences, tehran, iran ahmad mohammadi-farani department of pharmacology, school of medicine, tehran university of medical sciences, tehran, iran golnar karimian department of pharmacology, school of medicine, tehran university of medical sciences, tehran, iran

background: the renin-angiotensin system has an important role in hepatic inflammation and fibrosis. renin-angiotensin system blockade by angiotensinconverting enzyme (ace) inhibitors provides some protective effects against hepatic fibrogenesis. captopril as an ace inhibitor can decrease inflammatory mediators and attenuate hepatic fibrosis in the livers of bile duct ligated (bdl) rats. object...

Journal: :Hypertension 2008
Duncan J Campbell

The renin-angiotensin system (RAS) plays an important role in cardiovascular and renal physiology and disease, and the benefits of angiotensin-converting enzyme inhibitor, angiotensin type 1 receptor blocker, and renin inhibitor therapies are mediated in part by their modification of the levels and actions of angiotensin peptides. Despite its long history, the RAS remains an active area of rese...

Journal: :Clinics in Geriatric Medicine 2011

Journal: :Journal of Biological Chemistry 2010

Journal: :Nephrology Dialysis Transplantation 2004

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