Previous research in young subjects found that rapid eye movement (REM) density is higher in those REM phases which are followed by an awakening (REM-W) than in those preceding NREM (REM-N), suggesting a 'gating role' of REM sleep toward the awakening. It is not yet known whether this evidence is maintained in elderly subjects, who display, relative to young subjects, more awakenings, different...

Abstract Introduction Congenital central hypoventilation syndrome (CCHS) is a rare disorder of respiratory deficiency due to mutation in the PHOX2B gene. Clinical presentation may be mild certain individuals different levels ventilatory dysregulation. Methods We present findings exogenous challenge testing and polysomnography (PSG) performed on normocapnic adult female with late-onset (LO) CCHS...

Two types of neurons are involved in the regulation of rapid eye movement (REM) sleep, the REM-ON and the REM-OFF neurons. As the name suggests, the REM-OFF neurons cease firing during REM sleep and they are norepinephrinergic. It has been shown that cessation of these neurons is a pre-requisite for the generation of REM sleep and GABA shuts them off. Further, if these neurons do not shut off, ...

This study was carried out to examine the relationship between the charge on low density lipoproteins (LDLs) and lipid and clinical parameters in 104 asymptomatic dyslipidemic men and to identify biochemical and genetic factors that could contribute to the charge variability of LDL. LDL charge heterogeneity was evaluated by relative electrophoretic mobility (REM) on preformed 0.5% agarose gels ...

OBJECTIVE The existence of a rapid eye movement (REM)-specific sleep-disordered breathing (SDB) has been suggested based on the finding of an association between sleepiness and respiratory disturbances confined primarily to REM sleep. The aim of the study was to define the frequency and the clinical and polysomnographic features of REM SDB in a large clinical population. METHODS Anthropometri...

Transection, lesion and unit recording studies have localized rapid eye movement (REM) sleep mechanisms to the pons. Recent work has emphasized the role of pontine cholinergic cells, especially those of the pedunculopontine tegmentum (PPT). The present study differentiated REM sleep deficits associated with lesions of the PPT from other pontine regions implicated in REM sleep generation, includ...

STUDY OBJECTIVES The pattern and distribution of rapid eye movement (REM) sleep changes during development, yet there have been few studies of REM density in children. Although children with obstructive apnea syndrome (OSAS) obstruct primarily during REM sleep, the relationship between REM density and obstructive apnea has not been established for this population. We hypothesized that (i) REM d...

around 75% of civilians have experienced at least one traumatic event in their lives, and this number is considerably higher in many parts of the world, as well as in military veterans and first responders. of those exposed to trauma, 15-25% will develop posttraumatic stress disorder (ptsd).  ptsd extracts enormous economic, health, and quality of life cost. thus, it is critical to understand m...

the possibility of bringing action in rem, is a privilege recognized in common law particularly in the maritime regulations of common law countries .on this basis, plaintiff may, subject to specified conditions, bring action against some properties (ship, cargo,…) instead of their owners, in order to enforce many maritime claims and in the case of pronouncing judgment in his or her favor, the j...

acetylcholinesterase (ache) is a large glycoprotein that, aside from its known cholinolytic activity, co-exists with other transmitter systems and possesses other functions. in the present study, the effects of short-term rapid-eye-movement sleep deprivation (rem-sd) on ache activity in the anterior hypothalamic area have been investigated. using the flower-pot method, adult male albino rats we...