BACKGROUND Palliative irradiation of osteolytic lesions is a considerable component in the treatment for patients with multiple myeloma. In this study, we analyzed the efficacy of irradiation in these patients. PATIENTS AND METHODS We retrospectively analyzed 153 patients with multiple myeloma who were admitted to our department between 1989 and 2013. According to the staging system of Durie ...

INTRODUCTION Tonsillectomy is the one of the most common types of surgery in children, and is often accompanied by post-operative pain and discomfort. Methods of pain control such as use of non-steroidal anti-inflammatory drugs (NSAIDs), narcotics, and local anesthetics have been used, but each have their own particular side effects. In this study we investigated the effect of ketamine on post-...

Methodology Male piglets between 5 and 7 d of age were ear notched, weighed, then randomly selected into control (n = 700) and treatment (n = 700) groups and given an injection (IM) of either saline solution or Anafen (Ketoprofen injection 100 mg/mL 1 mL/50 kg body weight), respectively. A sample size calculation was performed to determine the number of piglets required to demonstrate a 225g/da...

BACKGROUND To investigate whether PPIs BID is superior to QD for treatment of GERD in a short time. METHODS We searched PubMed, Cochrane Library, Scopus, EMBASE, Ovid, EBSCO, and Web of Science databases (from 1998 to May 2016) to select RCTs, which compared the efficacy of PPIs BID versus QD for GERD. The primary outcomes were symptom relief or esophageal mucosal healing at weeks 4 and 8. Th...

This study was undertaken to investigate the contribution of a weight-relieving system on the gait of patients with severe locomotor disabilities. Temporal parameters of gait and subjective evaluations of the effect of the system were studied in 24 patients and 6 healthy subjects. Partial weight relief was accomplished through a pneumatic system mounted in the ceiling over a conductive walkway ...

The use of acupuncture as a method of pain relief in Western medicine is based on a wide range of clinical trials, and there is no doubt that it has significant effect in the treatment of acute and chronic pain, as to the pain classification. Acupuncture has been recognized as a pain relief method in most countries and is commonly used in general practice and at pain relief clinics in addition ...

BACKGROUND The study aimed to investigate the analgesic effect of a combination of intravenous flurbiprofen axetil and opioids, and evaluate the relationship between refractory pain relief and plasma β-endorphin levels in cancer patients. MATERIALS AND METHODS A total of 120 cancer patients was randomly divided into two groups, 60 patients took orally morphine sulfate sustained-release tablet...

Introduction: Thoracic segmental epidural analgesia despite its technical difficulty and time consumption provides better analgesia and has a beneficial effect on the post-operative pulmonary and metabolic function; immunological and stress response. Aims and Objectives: To study the efficacy of fentanyl for pain relief of inpatients after upper abdominal procedures and compare with bupivacaine...

OBJECTIVE To assess whether codeine and caffeine enhance the analgesic effect of aspirin in post-operative pain. METHOD Systematic overview of the literature and meta-analysis of published randomized controlled trials (RCTs). RESULTS Codeine 60 mg leads to a small increase in the analgesic effect of 650 mg of aspirin when total pain relief score (TOTPAR%) is used as a efficacy end-point. Th...