نتایج جستجو برای: relaxivity

تعداد نتایج: 880  

Journal: :Dalton transactions 2012
Elke Debroye Geert Dehaen Svetlana V Eliseeva Sophie Laurent Luce Vander Elst Robert N Muller Koen Binnemans Tatjana N Parac-Vogt

A ditopic DTPA monoamide derivative containing an 8-hydroxyquinoline moiety was synthesized and the corresponding gadolinium(III) complex ([Gd(H5)(H(2)O)](-)) was prepared. After adding aluminum(III), the 8-hydroxyquinoline part self-assembled into a heteropolymetallic triscomplex [(Gd5)(3)Al(H(2)O)(3)](3-). The magnetic and optical properties of this metallostar compound were investigated in o...

2009
V. Clavijo Jordan M. R. Caplan K. M. Bennett

Introduction: Targeted and smart molecular contrast agents have made it possible to detect events in the molecular scale in vivo (1). While many iron oxide based contrast agents with per ion T2 relaxivity of ~100mMs allow the detection of nM concentrations, common lanthanide chelates such as Gd-DTPA, with T1 relaxivity ~5mMs , require μM-mM concentrations, making the study of molecular events d...

Journal: :Journal of Cardiovascular Magnetic Resonance 2009

Background: Magnetic resonance imaging (MRI) using nanostructures has been a proper method for tumor targeting purposes. Different MRI nanomaterials, targeting agents and anticancer drugs have been used for targeting of tumors. Objectives: This study aims to consider the MRI property of doxorubicin (DOX)-loaded gadolinium/13X zeolite/folic acid (Gd3+/13X/FA) nanocomposite.<br /...

2015
Michael A. Bruckman Allen VanMeter Nicole F. Steinmetz

Nanomanufacturing of nanoparticles is critical for potential translation and commercialization. Continuous flow devices can alleviate this need through unceasing production of nanoparticles. Here we demonstrate the scaled-up production of spherical nanoparticles functionalized with biomedical cargos from the rod-shaped plant virus tobacco mosaic virus (TMV) using a mesofluidic, continued flow m...

Journal: :Chemical communications 2015
Oliver J Stacey Angelo J Amoroso James A Platts Peter N Horton Simon J Coles David Lloyd Catrin F Williams Anthony J Hayes Jay J Dunsford Simon J A Pope

Facile conjugation of a luminescent cyclometalated Pt(II) complex with a DO3A-derived Gd(III) moiety yields a hybrid species with visible luminescence and enhanced relaxivity.

Journal: :Chemical communications 2010
Kevin Guo Mikhail Y Berezin Jie Zheng Walter Akers Franck Lin Bao Teng Olga Vasalatiy Amir Gandjbakhche Gary L Griffiths Samuel Achilefu

A new gadolinium chelating NIR fluorescent molecular probe increases T(1) relaxivity of water protons, facilitating combined optical and magnetic resonance imaging.

Journal: :Dalton transactions 2015
Miguel F Ferreira Janaina Gonçalves Bibimaryam Mousavi Maria I M Prata Sérgio P J Rodrigues Daniel Calle Pilar López-Larrubia Sebastian Cerdan Tiago B Rodrigues Paula M Ferreira Lothar Helm José A Martins Carlos F G C Geraldes

The relaxivity displayed by Gd(3+) chelates immobilized onto gold nanoparticles is the result of the complex interplay between the nanoparticle size, the water exchange rate and the chelate structure. In this work we study the effect of the length of ω-thioalkyl linkers, anchoring fast water exchanging Gd(3+) chelates onto gold nanoparticles, on the relaxivity of the immobilized chelates. Gold ...

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