background: it is now well-demonstrated that histone demethylases play an important role in developmental controls, cell-fate decisions, and a variety of diseases such as cancer. lysine-specific demethylase 5d (kdm5d) is a male-specific histone demethylase that specifically demethylates di- and tri-methyl h3k4 at the start site of active genes. in this light, the aim of this study was to invest...

UNLABELLED Bacterial cells monitor their environment by sensing a set of signals. Typically, these environmental signals affect promoter activities by altering the activity of transcription regulatory proteins. Promoters are often regulated by more than one regulatory protein, and in these cases the relevant signals are integrated by certain logic. In this work, we study how single amino acid s...

TAMPERE UNIVERSITY OF TECHNOLOGY Master's Degree Programme in Communications Electronics ANTTI HÄKKINEN: Simulating Evolutionary Processes of Stochastic Genetic Networks in Volatile Environments Master of Science Thesis, 66 pages November 2011 Major: Signal Processing Examiners: Professor Olli Yli-Harja, Assistant Professor Andre Ribeiro