Background: Hypothyroidism is associated with dysfunction of the bone turnover with reduced osteoblastic bone formation and osteoclastic bone resorption. Mesenchymal stem cells (MSCs) secrete various factors and cytokines that may stimulate bone regeneration.  The aim of this study was to determine the effects of MSCs-conditioned medium (CM) in hypothyroidism male rats after inducing bone ...

T H E failure of de novo regeneration of extirpated bones in adult urodeles has been described repeatedly. Wendelstadt (1901) reported the absence of skeletal regeneration following the removal of either the ulna or radius from the otherwise intact limbs of salamanders. Reed (1903) and Morrill (1918) likewise failed to obtain regeneration of previously excised fibulae in salamander hind limbs. ...

context this article reviews the available evidence about the barrier membranes utilized in guided tissue regeneration process to prevent the migration of unfavorable cells to the wound area. evidence acquisition available evidence about membranes properties and their different uses were reviewed, and the results of clinical and animal studies and systematic reviews were gathered. results a lar...

Narrow alveolar ridges remain a serious challenge for the successful placement of endosseous implants. This article reports a technique for widening the atrophic ridge by splitting the alveolar bone longitudinally and filling the bone gap with collagenised pig bone, treatment of ridges as thin as 2.5mm at the alveolar crest and simultaneous placement of dental implants. Treatment of a 22-year-o...

Complete retinal regeneration in adult animals occurs only in certain urodele amphibians, in which the retinal pigmented epithelial cells (RPE) undergo transdifferentiation to produce all cell types constituting the neural retina. A similar mechanism also appears to be involved in retinal regeneration in the embryonic stage of some other species, but the nature of this mechanism has not yet bee...

Is active restoration the best approach to achieve ecological restoration success (the return to a reference condition, that is, old-growth forest) when compared to natural regeneration in tropical forests? Our meta-analysis of 133 studies demonstrated that natural regeneration surpasses active restoration in achieving tropical forest restoration success for all three biodiversity groups (plant...

in cartilage regeneration in the temporomandibular joint, although those are somehow effective for a variety of cells 2. Despite such promising clinical successes of GFs for tissue regeneration, controversies still hound their clinical use for tissue regeneration of the oral and maxillofacial area. The biggest debate deals with the oncogenic potential of GFs. Many tumors including malignancies ...

background: many people suffer from nerve injury. the time consuming nature of the treatments makes the condition worse. therefore, finding a way to accelerate the process of nerve repair is very important. objective: to determine the effect of ultrasound on the acceleration of crushed peripheral nerve regeneration. methods: the experimental model included crushed rat’s sciatic nerve. 40 rats w...