Chang′E-2 (CE-2) lunar orbiter is the second robotic orbiter in the Chinese Lunar Exploration Program. The chargecoupled-device (CCD) camera equipped on the CE-2 orbiter acquired stereo images with a resolution of less than 10 m and global coverage. High-precision topographic mapping with CE-2 CCD stereo imagery is of great importance for scientific research, as well as for the landing preparat...

Malignant hyperthermia (MH) is an autosomal dominant disorder presenting under general anaesthesia. It is occasionally associated with a myopathy, central core disease (CCD), named after its predominant histochemical characteristic. The penetration of CCD is variable, but typically affected individuals show delayed motor milestones in infancy and remain physically compromised. It was thought un...

As three-chip hybrids, the amplifiers have from the start been designed to solve economically the problems that up to now have limited the use of off-the-shelf units. Key to keeping costs down is a capacitive-coupling approach to isolation. Any amplifiers so far available with the same capabilities are costly, enlisting magnetic or optical techniques to bridge the high-voltage barrier. Whether ...

Little is known about collecting duct adenylyl cyclase (AC) isoforms or regulation in the mouse. We performed RT-PCR for AC isoforms 1-9 in microdissected cortical (CCD) and outer medullary (OMCD) and acutely isolated inner medullary (IMCD) collecting duct. All collecting duct regions contained AC3, AC4, and AC6 mRNA, while CCD and OMCD, but not IMCD, also contained AC5 mRNA. Acutely isolated I...

K(+) channels in the basolateral membrane of mouse cortical collecting duct (CCD) principal cells were identified with patch-clamp technique, real-time PCR, and immunohistochemistry. In cell-attached membrane patches, three K(+) channels with conductances of approximately 75, 40, and 20 pS were observed, but the K(+) channel with the intermediate conductance (40 pS) predominated. In inside-out ...

1 The PETM represents one of the largest and most abrupt greenhouse warming events in Earth’s history. Marine and terrestrial records document a global >2.5‰ negative carbon isotope excursion (CIE; refs 1–3) coincident with global mean surface ocean warming of >4 °C (ref. 4) and geochemical and sedimentological evidence for ocean acidification5,6. Collectively, these lines of evidence suggest a...

BACKGROUND Although attritive and abrasive wear of recent composite resins has been substantially reduced, in vitro wear testing with reasonably simulating devices and quantitative determination of resulting wear is still needed. Three-dimensional scanning methods are frequently used for this purpose. The aim of this trial was to compare maximum depth of wear and volume loss of composite sample...

The accurate measurement of the position of celestial objects is a fundamental step for several astrophysical investigations. For ground based instruments, the atmosphere is considered the basic limiting factor; in space, the knowledge of the instrumental parameters and/or of their stability define the performance limits, but CCD cameras operated in time delay integration may take advantage of ...

Cleidocranial dysplasia (CCD) is an autosomal dominant inheritable skeletal disease caused by heterozygous mutations in an osteoblast-specific transcription factor, RUNX2. Mutational analyses of RUNX2 were done on 4 unrelated Chinese patients with CCD. One nonsense and 3 missense mutations were detected, including one novel mutation, a heterozygous G to C transition mutation at nucleotide 475 i...