The term "progestagens" covers a group of molecules including both the natural female sex hormones Progesterone and 17-hydroxy Progesterone as well as several synthetic forms, all displaying the ability to bind Progesterone receptors. Several studies have used Progesterone and related steroids in the attempt to prevent spontaneous miscarriage, and treat recurrent miscarriage. The present paper ...

To study the association of chromosomal polymorphic variations with recurrent miscarriage. Recurrent miscarriage becomes a problem that affect an increasing number of couples with the frequency of about 1% in the couples who want to conceive. This study is based on comparison of chromosome Heteromorphism in the karyotypes of two groups. The first group with 400 individuals with the history of m...

BACKGROUND Recurrent miscarriage is generally defined as three or more miscarriages before gestational week 20. Recurrent miscarriage affects 1% of all women and the condition can only be explained by parental chromosome abnormalities, uterine malformations, or endocrine or thrombophilic disturbances to a limited extent. Immunological disturbances are hypothesised to play an important role in r...

Maternal effect genes control early events of embryogenesis. Maternal homozygous and compound mutations in two such genes, NLRP7 and c6orf221, have been detected in the majority of women experiencing recurrent biparental hydatidiform moles. It was suggested that other forms of reproductive wastage, including diploid androgenetic moles, partial moles, polyploidy, recurrent spontaneous abortions ...

In the present study determine the level of serum anticardiolipin (ACL) antibodies (ACLIgM and ACL-IgG) in 30 pregnancies women who clinically diagnosed with recurrent miscarriage more than two times their aged between 21– 42 years, attending to Babylon hospital of maternity and children and 15 healthy pregnant women without previous miscarriage were included as control in the study which exten...

Background: Recurrent miscarriage (RM) is defined as two or more consecutive pregnancy losses before 20 weeks of gestation as an important clinical problem, with an incidence of 1-3% among couples wishing to have children. There are several factors in the etiology of recurrent miscarriage. One of the main genetic causes which involve in the pathogenesis of RM is balanced chromosomal rearrangeme...

Recurrent miscarriage is a less recognized feature of Wilson’s disease and adequate treatment can alter the outcome of pregnancies favourably. Wilson’s disease is a recessively inherited disorder of copper metabolism due to mutations in the ATP7B gene, which encodes for a coppertransporting P-type ATPase. Recurrent miscarriage is a complication of untreated Wilson’s disease. It has been reporte...