The onset of the spontaneous LH surge in women is relatively abrupt with concentrations doubling within 2 h to between 100 and 200 IU/l being sustained for 12–14 h over a mean duration of 50 h [1]. This mid-cycle surge, in addition to follicular rupture [2], promotes several periovulatory events including disruption of the oocyte– cumulus oophorus cell contact and induction of the resumption of...

Gonadotropins are routinely administered to produce multiple oocytes for clinical in vitro fertilization (IVF) treatment, laboratory research, and livestock industries. Studies in mice have shown gonadotropin stimulation using equine chorionic gonadotropin (eCG) affects the endometrium, implantation, and fetal development. Evidence from clinical studies also indicates that stimulation with reco...

Conception is rare in patients on chronic dialysis and diagnosis is often delayed as it is least expected. Serum beta HCG levels are elevated in both pregnant and non-pregnant dialysis patients, and pregnant dialysis patients have slightly higher beta HCG levels when compared with normal pregnancy. This can be erroneously interpreted as non-viable pregnancy and so results should be viewed with ...

Plasma membranes isolated from bovine corpora lutea showed specific binding with 1251-human chorionic gonadotropin and 1251-human luteinizing hormone; unlabeled hormones competitively inhibited the binding. The binding of the 1251-human chorionic gonadotropin to the receptor was a saturable phenomenon and the half-saturation was attained at a concentration of 4 X lo-r0 M. Maximum hormone recept...

BACKGROUND Rh glycoproteins (RhAG, RhBG, RhCG) are members of the Amt/Mep/Rh family which facilitate movement of ammonium across plasma membranes. Changes in ammonium transport activity following expression of Rh glycoproteins have been described in different heterologous systems such as yeasts, oocytes and eukaryotic cell lines. However, in these complex systems, a potential contribution of en...

background: spontaneous ovarian hyperstimulation syndrome rarely occurs during pregnancy and is usually associated with high levels of human chorionic gonadotropin, in conditions such as molar or multifetal pregnancies. case report: here we report spontaneous ovarian hyperstimulation in a patient presenting with missed abortion at 16th week of gestation, when serum ß-subunit human chorionic gon...

We report the case of a 22-year-old male who had a history of metastatic right testicular tumor successfully treated with chemotherapy and surgery. Twenty-one months after the initial treatment, the serum human chorionic gonadotropin started to increase gradually, but whole body imaging including the left testis revealed no abnormal finding except testicular microlithiasis. A biopsy of the left...

background: the value of serial measurement of serum ß subunit of human chorionic gonadotropin (ßhcg) and ultrasonography in the early diagnosis of ectopic pregnancy has well established. objective: the objective of this study was to explore the diagnostic value of raising level of serum ßhcg, single measurement of progesterone (p) and estradiol (e2) in early diagnosis of ectopic pregnancy. mat...

A young woman with an occult bronchogenic carcinoma presented with secondary amenorrhea and an elevated beta subunit of human chorionic gonadotropin that was mistakenly attributed to pregnancy. Physicians should be aware that this carcinoma may present solely with an elevated beta human chorionic gonadotropin value, and the potential exists for confusion with a pregnancy state in women of child...

A highly active preparation of human chorionic gonadotropin has been obtained by simple methods of column chromatography on diethylaminoethyl Sephadex and Sephadex G-100. The preparation appeared homogeneous by disc and immunoelectrophoresis, ultracentrifugation, and end group analysis. It assayed at 12,000 i.u. per mg by the rat prostrate gland and accessory sex organ method. The ~20,~ value w...