A newly developed autofluorescence (AF) imaging technique was applied during colonoscopy in a clinical setting. This pilot study was conducted to evaluate the clinical feasibility of applying AF endoscopy for distinguishing colorectal lesions. A total of 54 colorectal mucosal lesions obtained from 43 patients who underwent both white-light and AF endoscopy and were treated by endoscopy or surger...

Aim: Sessile serrated lesions (SSL) have the potential for malignant transformation into colorectal carcinoma (CRC), which develops via pathway of carcinogenesis. Material and Methods: Based on colonoscopy pathology reports, all sessile or polyps in risk screening group were studied at an urban medical research center between July 2018 2022. We prospectively included consecutive classified as a...

background: endometrial cancer is the most common gynecologic malignancy that has often proceeded by a premalignant phase. modern molecular and immune staining methods for precancerous lesions diagnosis have been expanded. one of the genetic alternations in the endometrial cancer carcinogenesis is the mutational activation of the k-ras oncogene. k-ras mutation has recognized to occur at an earl...

A broad spectrum of lesions, including hyperplastic, metaplastic, inflammatory, infectious, and reactive, may mimic cancer all along the urinary tract. This narrative collects most them from a clinical pathologic perspective, offering urologists general pathologists their salient definitory features. Together with classical, well-known, entities such as urothelial papillomas (conventional (UP) ...

BACKGROUND AND AIMS Reactive hyperplastic lesions of the oral connective tissue are associated with injuries of soft tissue and have high prevalence rates and different involvement patterns in different parts of the world. The aim of this study was to analyze demographic data of a university department. MATERIALS AND METHODS Patient records of the Department of Oral Pathology during a four-ye...

background: few studies regarding oral lesions of children and adolescents were reported in the medical literature. the aim of this study was to determine the frequency of these lesions in patients from birth to 20 years old in babol, northern iran.methods: the slides of all cases of oral lesions in children and adolescents, between 1990 and 2012 were obtained from the pathology archives of sha...

The method to reveal DNA-instability as demonstrated by immunohistochemical staining with anti-cytidine antibody after acid hydrolysis (DNA-instability test) was used as a marker of malignancy. The test was applied to paraffin-embedded sections taken from 15 urinary bladders, renal pelvic cavities, and ureters bearing multiple carcinoma in situ (CIS) and totally 31 papillary urothelial cancers....

An 81-year-old woman presented for colonoscopy because of iron deficiency anemia. She had undergone colonoscopy 5 years previously during which a 2-cm prominent fold had been identified in the proximal ascending colon (●" Fig.1). A biopsy of this lesion was interpreted as being a hyperplastic polyp (●" Fig.2), although the polyp showed features of a serrated lesion. Because of clinical concern ...

BACKGROUND The migration and proliferation of myofibroblasts are prominent features of myointimal hyperplasia associated with haemodialysis polytetrafluoroethylene (PTFE) grafts. Since C-reactive protein (CRP) possesses functional activities on vascular smooth muscle cells (SMCs), we examined the expression of this protein in PTFE grafts early in the course of myointimal hyperplasia development...