Abstract Introduction Acetylcholine (ACh) spasm provocation testing together with the diagnostic criteria published by Coronary Vasomotor Disorders International Study Group (COVADIS) are considered gold standard for diagnosis of coronary vasospasm in contemporary clinical practice. In 20–29% patients undergoing an equivocal test result occurs when these only partially met and poses a dilemma. ...

An experimental model of’ ischaemic colitis was produced in 14 rhesus monkeys by complete vascular occlusion to the splenic flexure for periods varying from 4 to 8.5 hours. Clinical assessment of bowel viability following revascularization was inaccurate in 10 monkeys. Reactive hyperaemia was quantitatively measured using 99mtechnetium-tagged albumin microspheres and this correlated well with a...

The aim of the present study was to evaluate changes in cutaneous blood flow detected by incoherent optical fluctuation flowmetry (IOFF) diabetic patients with diagnosed microangiopathies. includes 52 type 2 diabetes mellitus (12 males, 40 females, median age 57 (51; 60) years). All were examined using IOFF method functional tests: occlusion test on index finger, local heat dorsum foot, and big...

Patients with classical migraine whose auras included paraesthesiae or numbness in the hands have been reviewed. In 55 of 111 patients the symptoms were on the same side of the body as the headache and in only 20 on the opposite side to the headache. In the remaining 36 patients one or other was incompletely lateralised. Five right handed patients described dysphasia at the same time as paraest...

C oronary pressure derived fractional flow reserve (FFR) is an increasingly used invasive index of the functional significance of coronary lesions. FFR expresses maximum achievable blood flow to the myocardium, supplied by a stenotic artery, as a fraction of normal maximum flow. 2 Achievement of maximal hyperaemia is essential for calculation of FFR. Intracoronary adenosine is widely used to ob...

Following experimental inoculation of 3-week-old turkeys with different titres (106, 104, 103, 102 and 101 egg infectious dose (EID50)) of A/ostrich/Italy/984/2000 H7N1 highly pathogenic avian influenza virus (HPAIV), the selected tissues and organs were examined for pathological changes. Tissue samples from different organs that obtained from dead and sacrificed birds were fixed in 10% neutral...