The effect that growth has on dual-energy x-ray absorptiometry (DXA) bone measurements is yet to be fully defined. The purpose of this study was to determine the best method for optimizing pediatric bone measurements using DXA. Height, weight, body mass index, skeletal age, and Tanner stage of sexual development were determined for 64 healthy boys and 60 healthy girls ages 6-17 yr. DXA of the l...

INTRODUCTION Studies of obesity require the estimation of fat mass (FM) and fat-free mass (FFM); therefore it is important to validate methods that evaluate these measurements. OBJECTIVE We sought to compare two different bioelectrical impedance analysis systems (BIAs) to estimate FM and FFM using dual-energy X-ray absorptiometry (DXA) as reference. METHODS We used a cross-sectional design....

Dual-energy X-ray absorptiometry (DXA; DEXA) is the technique of choice to diagnose osteoporosis and to monitor the response to treatment. It is also useful for measuring body composition. In recent years, new applications have been developed, including vertebral morphometry through the study of the lateral spine, prosthesis integration in orthopedics, and lipodystrophy in HIV+ patients, althou...

BACKGROUND AND OBJECTIVES Vascular calcification (VC) contributes to increased cardiovascular (CV) disease in dialysis patients and is inversely correlated with bone mineral density (BMD). Screening for VC may determine patients at greater CV risk and bone densitometry may have dual role in assessing VC as well as BMD. The aim of this study was to determine measurement of VC using dual-energy x...

BACKGROUND According to the WHO, osteoporosis is one of the most important non- communicable diseases worldwide. Different screening procedures are controversially discussed, especially concerning the concomitant issues of overdiagnosis and harm caused by inappropriate Dual X-ray Absorptiometry (DXA). The aim of this study was to evaluate the frequency and appropriateness of DXA as screening me...

The principal use of dual-energy X-ray absorptiometry (DXA) is to diagnose and monitor osteoporosis and therefore reduce fracture risk, associated morbidity, and mortality. In the field of rheumatology, DXA is an essential component of patient care because of both rheumatologists' prescription of glucocorticoid treatment as well as the effects of rheumatological diseases on bone health. This re...

BACKGROUND Total body volume (TBV), with the exclusion of internal air voids, is necessary to quantify body composition in Lohman's 4-compartment (4C) model. OBJECTIVE This investigation sought to derive a novel, TBV measure with the use of only dual-energy X-ray absorptiometry (DXA) attenuation values for use in Lohman's 4C body composition model. DESIGN Pixel-specific masses and volumes w...

The aim of this 2-year longitudinal observational study was to explore hand bone loss as a disease outcome measure in established rheumatoid arthritis (RA). A cohort of 215 patients with RA (170 women and 45 men, aged 20-70 years) were recruited from the Oslo RA registry and studied for changes in hand bone mass during a 2-year follow-up. Digital X-ray radiogrammetry (DXR) was used to measure c...

We thank the Editor for opportunity to respond Letter Editor: “Concerns regarding use of 3D-DXA” in relation our recent publication, Harding et al., Bone, 136, 2020, 115,362. The author writes “It is my understanding that it not possible measure cortical parameters from a two-dimensional dual-energy X-ray absorptiometry (DXA) image.” This correct. Technically, all so-called ‘measures’ indirec...

BACKGROUND AND OBJECTIVES Currently, there is no consensus whether dual-energy X-ray absorptiometry (DXA) or quantitative computed tomography (QCT) can be used to screen for osteoporosis or osteopenia in CKD-5D patients. This study uses iliac bone histology, the "gold standard" for bone volume evaluation, to determine the utility of DXA and QCT for low bone mass screening in CKD-5D patients. ...