A new chip-based crystal-mounting approach for rapid room-temperature data collection from numerous crystals is described. This work was motivated by the recent development of X-ray free-electron lasers. These novel sources deliver very intense femtosecond X-ray pulses that promise to yield high-resolution diffraction data of nanocrystals before their destruction by radiation damage. Thus, the ...

This paper analyses a discrete-time (s, S) queueing inventory model with service time and back-order in inventory. The arrival of customers is assumed to be the Bernoulli process. Service follows geometric distribution. As soon as level reaches pre-assigned due demands, an order for replenishment placed. Replenishment also When reduces zero or non-replenishment items, maximum k are allowed syst...

AIMS Glycosaminoglycan (GAG) layer replenishment is a cornerstone in the therapy of interstitial cystitis (IC). During the last years intravesical GAG layer replenishment has proven to be an effective treatment for overactive bladder (OAB), radiation cystitis, and recurrent urinary tract infections (UTIs). METHODS Examination of different substances available for intravesical GAG replenishmen...

Joint replenishment problem (JRP) is a common real problem which aims to minimize order cost and inventory holding cost. In this paper, classical, centralized and decentralized JRP models are discussed. An innovative heuristic to minimize the total cost is implemented for each model. This heuristic seeks to balance the order cost and the inventory holding costs. The results show that the innova...

We consider the diffusive motion of a particle performing a random walk with Lévy distributed jump lengths and subject to a resetting mechanism, bringing the walker to an initial position at uniformly distributed times. In the limit of an infinite number of steps and for long times, the process converges to superdiffusive motion with replenishment. We derive a formula for the mean first arrival...

Although vesicle replenishment is critical in maintaining exo-endocytosis recycling, the underlying mechanisms are not well understood. Previous studies have shown that both rapid and slow endocytosis recycle into a very large recycling pool instead of within the readily releasable pool (RRP), and the time course of RRP replenishment is slowed down by more intense stimulation. This finding cont...

This paper examines a single-period inventory problem with random capacity and demand, where the loss-averse preference is adopted to describe the newsvendor’s decision-making behavior. When the loss-averse newsvendor orders, the supplier has some random replenishment capacity. He will choose an order quantity to maximize his expected utility. The newsvendor’s optimal ordering policy is obtaine...

In this paper, the cost function for a three-echelon inventory system with two warehouses is derived. Transportation times are constant and retailers face independent Poisson demand. Replenishments are one-for-one. The lead time of a retailer is determined not only by the constant transportation time but also by the random delay incurred due to the availability of stock at the warehouses. We co...