In a series of 156 thyrotoxic patients treated with low doses of radioactive iodine the therapeutic dose was calculated by means of a sliding scale in which the dose level was varied according to the estimated size of the gland. Of the patients so treated 56.5% achieved a remission with a single dose of (131)I. The incidence of hypothyroidism at one year was 5%.

et al.4 Moreover, because of its slow elimination amiodarone would inhibit uptake of radioactive iodine for months. Although amiodarone has been reported to cause thyrotoxicosis, this appears to be rare,3 probably occurring only in subjects with associated iodine deficiency (Jod-Basedow effect). Thus amiodarone controls thyrotoxicosis clinically and biochemically but has no advantages over equi...

to its glycoside (arachidoside) content. On the basis of in creased excretion of phenols in the group of rats fed arachi doside, and of an increased iodine content in the phenolic fraction of the urine as compared with the control, it was sug gested that this glycoside acted as an antithyroid compound by forming molecular compounds with elemental iodine in the gland. Confirmatory evidence for t...

RADIOACTIVE iodine (iodine-131) has been used extensively during the past 30 years for the treatment of hyperthyroidism and has been shown to control this disorder in the majority of cases in which it has been used. There have been varying reports of the incidence of post-radiation hypothyroidism which has been reported to be as high as 70 per cent in patients followed up for 10 years (Beling a...

We evaluated the incidence of childhood thyroid diseases and urinary iodine levels in Nagasaki, Japan and in Gomel, Belarus, which was greatly radio-contaminated by the Chernobyl accident, in order to obtain the comparative data of thyroid diseases between iodine-rich (Japan) and -deficient (Belarus) areas. In Nagasaki, the median level of urinary iodine, measured by ammonium persulfate digesti...

On 11 March 2011, the Fukushima nuclear disaster shocked the world. A 9.0 magnitude earthquake induced a tsunami, which then shut down the power supply of cooling system of the nuclear plant. The nuclear reactor exploded due to overheat and hydrogen accumulation. Radioactive materials were released and plutonium was detected positive in the soil of the power plant. It is the most severe nuclear...