Purpose: The present study aimed to investigate the effect of immobilization stress on the induction of diabetes mellitus in rats. Materials and Methods: In this experimental study 30 mature male rats with an average weight of 200-220 gr were randomly divided into three groups of ten each. Group I served as the control while the experiment groups were Group II (10 days) and Groups III (30 d...

background and aims: some nanoparticles can be used in immunoassays to increase sensitivity. this study aimed to evaluate a novel nano-immunoassay based on bovine serum albumin nanoparticles (bsa nps). materials and methods: at first, the nanostructure was synthesized, and then applied as a tag in the nano-immunoassay. then the concentration of β-subunit of human chorionic gonadotropin (βhcg) i...

there are increasing evidences that show many xenobiotic chemicals (called as endocrine disruptorchemicals edcs) through interfering with endocrine system, have the capability to induce developmentaland reproductive abnormalities in humans and animals. the yolk protein precursor vitellogenin (vtg) hasproved to be a simple and sensitive biomarker for assessing exposure of fish to edcs especially...

adequate intake of folate has an important role in the prevention of nutritional anemia and other complications in childbearing age women. this study was undertaken to determine dietary folate intake and concentration of folate in serum and red blood cell (rbc) in female students of a medical university in tehran, the capital of iran.  in this cross sectional study, 346 female students were ran...

reply to the letter sent by prof. viroj wiwanitkit entitled “radiofrequency radiation and human ferritin”   authors of the article entitled “effects of radiofrequency radiation on human ferritin: an in-vitro enzymun assay” [1] would like to express their satisfactions, since the manuscript have been accessed and used as an element of reflection by a renowned researchers such as prof. wiwanitkit...

Methods 1. To amplify the Adenovirus Expressing TSHR A-subunit (Ad-TSHR-289) and the control adenovirus (Ad-b-gal); 2. Female Balb/c mice aged 6 weeks were divided randomly into the experimental group and the control group, then injected intramuscularly with Ad-TSHR-289 (3.3×10PFU/50μlPBS) and the control adenovirus(Adb-gal 3.3×10 PFU /50μlPBS) three times at 3 weeks intervals. 3. In 1 wk after...

BACKGROUND Little information is available on leptin concentrations in individuals with IGT. This study aims to determine and correlate leptin levels to anthropometric measures of obesity in pre-diabetic, (IFG and IGT), type 2 diabetic and normoglycaemic Saudis. METHODS 308 adult Saudis (healthy controls n = 80; pre-diabetes n = 86; Type 2 diabetes n = 142) participated. Anthropometric parame...

A sensitive enzyme immunoassay (EIA) specific for hepatitis B virus core antigen (HBcAg) and hepatitis B e antigen (HBeAg) was developed. We designated the precore/core gene products as hepatitis B virus (HBV) core-related antigens (HBcrAg). In order to detect HBcrAg even in anti-HBc/e antibody-positive specimens, the specimens were pretreated in detergents. The antibodies are inactivated by th...

CONTEXT Viral hepatitis diagnosis is an important issue in the treatment procedure of this infection. Late diagnosis and delayed treatment of viral hepatitis infections can lead to irreversible liver damages and occurrence of liver cirrhosis and hepatocellular carcinoma. A variety of laboratory methods including old and new technologies are being applied to detect hepatitis viruses. Here we hav...