The bioactive ingredients of sea cucumber Holothuria moebii were investigated, and four sulfated saponins (1-4) and one desulfated saponin (3B) with an unusual 3,4-epoxy xylose were obtained from this study. Compound 2 is a new triterpenoid saponin and 3B is a new artificial compound. On the basis of the extensive NMR and HRESIMS data, their structures were assigned as 3-O-[β-D-quinovopyranosyl...

To facilitate effective resource utilization, we have investigated triterpene saponins such as saikosaponin from the aerial parts of Bupleurum (B.) falcatum L., which are commonly discarded. Seven oleanene saponins were isolated from this plant; they were classified as the 13,28-epoxy type, 12-ene type, 9(11),12-diene type, and 28-acid type on the basis of their structural characteristics. For ...

In the present work the effect of quercetin obtained from (Allium cepa). Albizzia lebbek (crude extract of seeds) and a pure saponin fraction of Albizzia has been studied on the mast cells in the mesentery and peritoneal fluid of rats subjected to anaphylaxis. The results show a mast cell membrane stabilizing effect of these test drugs.

Panax ginseng is one of the most important medicinal plants in Asia, particularly Korea. Triterpene saponins (ginsenosides) are the main bioactive compounds in P. ginseng. The present study investigates the growth characteristics and variation of ginsenoside content in the leaves and roots of Korean ginseng (Panax ginseng) at different growth stages (from 1 to 6 years). Variation in ginsenoside...

OBJECTIVES The immunoadjuvant potential of cross-linked dextran microspheres (CDM) as absorption enhancer and Quillaja saponins (QS) as immunomodulator adjuvant was evaluated. MATERIALS AND METHODS CDM loaded or tetanus-mixed toxoid (TT) or Quillaja saponin (QS) were nasally administered to rabbits in dry powder form, three times in 2 weeks interval and serum IgG and nasal lavage sIgA titers ...

Broberg, S. Studies of Oligoand Polysaccharides by MALDI-TOF and ESI-IT MS Mass Spectrometry. Doctor’s dissertation. ISSN 1401-6249, ISBN 91-576-6465-X This thesis presents methods for analyzing carbohydrates with matrix-assisted laser desorption/ionization time-of-flight, MALDI-TOF, and electrospray ionization ion trap multiple-stage, ESI-IT MS, mass spectrometry, MS. MALDI-TOF MS was employed...

Saponins have been considered as promising natural substances for mitigating methane emissions from ruminants. However, studies reported that addition of saponin-rich sources often arrived at contrasting results, i.e. either it decreased methane or it did not. The aim of the present study was to assess ruminal methane emissions through a meta-analytical approach of integrating related studies f...

In the context of a more sustainable economy, bio-surfactants become increasingly important, due to their independence petrol-based chemistry, usually mild synthesis conditions, and in certain cases pharmacological activity. We have recently discussed self-assembly studies binary systems microbial origin, or saponins extracted from plants (Hellweg et al., Frontiers Soft Matter, 2023, 2). presen...

Saponins from the seeds of C sinensis var. sinensis (tea seed saponins) have been well investigated. Their sapogenins, theasapogenols A, B, C, D, and E, were isolated and identified by Yosioka et al.i-3) Two major tea seed saponins, theasaponins Ei and E2, have also been recently determined,4) Saponins from the leaves of C sinensis var. sinensis (tea leaf saponins) were first studied by Machida...

Three new cycloartenol triterpene saponins, named shengmaxinsides A-C, have been isolated from the ethyl acetate soluble fraction of an ethanol extract of Cimicifuga simplex Wormsk roots. Their structures were established by chemical tests and detailed spectroscopic analysis as 25-O-acetyl-7,8-didehydrocimigenol-3-O-β-D-galactopyranoside (1), 7,8-didehydrocimigenol-3-O-β-D-galactopyranoside (2)...