نتایج جستجو برای: quality oocyte

تعداد نتایج: 766179  

2015
Assaf Ben-Meir Eliezer Burstein Aluet Borrego-Alvarez Jasmine Chong Ellen Wong Tetyana Yavorska Taline Naranian Maggie Chi Ying Wang Yaakov Bentov Jennifer Alexis James Meriano Hoon-Ki Sung David L Gasser Kelle H Moley Siegfried Hekimi Robert F Casper Andrea Jurisicova

Female reproductive capacity declines dramatically in the fourth decade of life as a result of an age-related decrease in oocyte quality and quantity. The primary causes of reproductive aging and the molecular factors responsible for decreased oocyte quality remain elusive. Here, we show that aging of the female germ line is accompanied by mitochondrial dysfunction associated with decreased oxi...

Journal: :Human reproduction 2001
E H Ng E Y Lau W S Yeung P C Ho

Previous studies have demonstrated that the use of recombinant human follicle stimulating hormone (rhFSH) for ovarian stimulation may be associated with a better outcome than human menopausal gonadotrophin (HMG), probably due to the absence of LH, higher FSH bioactivity and better quality of oocytes and embryos when rhFSH is used. Very few studies have examined the effects of different gonadotr...

2017
Tao Wang Ying-Ying Gao Li Chen Zheng-Wen Nie Wei Cheng Xiaoyan Liu Heide Schatten Xia Zhang Yi-Liang Miao

Oxidative stress is known as a major contributing factor involved in oocyte aging, which negatively affects oocyte quality and development after fertilization. Melatonin is an effective free radical scavenger and its metabolites AFMK and AMK are powerful detoxifiers that eliminate free radicals. In this study, we used porcine oocytes to test the hypothesis that melatonin could scavenge free rad...

Journal: :Molecular human reproduction 2014
Rémi Labrecque Marc-André Sirard

Various morphological and cytological traits of oocytes and their surrounding cumulus cells may be used to select oocytes for assisted reproduction. However, even with careful selection, successful IVF and subsequent embryo development remain uncertain. The factors that ensure oocyte competence are unclear and other approaches to assessing developmental potential must be explored. With the cons...

Ajina M, Chaouache N Kacem O Meddeb S Saad A Saidi H Tabka Z Zaouali Ajina M Zbidi A

Background: The aim of our study was to determine the metabolic profile: glucose, triglycerides (TG), high density lipoprotein (HDL) and cholesterol (CHT) in women undergoing ART (Assisted reproductive technology) cycles and estimate its effect on In Vitro Fertilization (IVF) outcomes Materials and Methods: Forty three women undergoing IVF treatment were included in the study. Patients were all...

Journal: :Human reproduction 2011
P Comizzoli B S Pukazhenthi D E Wildt

BACKGROUND Chromatin configuration of the germinal vesicle (GV) and quality of the cytoplasm are critical factors in achieving oocyte meiotic and developmental capacity during folliculogenesis. Besides gaining new insights into the timing and cellular mechanisms associated with the acquisition and regulation of GV oocyte competence, the domestic cat model was used to examine (i) the relation be...

Journal: :Human reproduction 2010
T Adriaenssens S Wathlet I Segers G Verheyen A De Vos J Van der Elst W Coucke P Devroey J Smitz

BACKGROUND Gene expression of cumulus cells (CC) could predict oocyte developmental quality. Knowledge of the genes involved in determining oocyte quality is scanty. The aim was to correlate clinical and biological characteristics during ovarian stimulation with the expression of 10 selected genes in CC. METHODS Sixty-three ICSI patients were stimulated with GnRH-agonist plus highly purified ...

2015
I. Gilbert A. Macaulay C. Robert

In vitro embryo production is the cornerstone of infertility treatment in human and is increasingly used in cattle to propagate high genetic merit animals. To increase its efficiency, many different approaches have been tested all of which stem from the concepts of oocyte quality and developmental competence. Presented here are recently reported findings and perspectives related to bovine oocyt...

Journal: :Reproduction 2013
Tessa Lord R John Aitken

With extended periods of time following ovulation, the metaphase II stage oocyte experiences deterioration in quality referred to as post-ovulatory oocyte ageing. Post-ovulatory ageing occurs both in vivo and in vitro and has been associated with reduced fertilization rates, poor embryo quality, post-implantation errors and abnormalities in the offspring. Although the physiological consequences...

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