OBJECTIVE Quality of life (QoL) is impaired in hypopituitary patients and patients with primary adrenal insufficiency. The aim of this study was to analyse the impact of glucocorticoid (GC) replacement on QoL. The main hypothesis was that ACTH-insufficient patients experience a dose-dependent deterioration in QoL. DESIGN, PATIENTS AND METHODS This was a retrospective analysis of data from KIM...

OBJECTIVE The aim of this study was to measure quality of life (QOL) impairment in individuals currently suffering from Graves' ophthalmopathy (GO) and to determine the correlation of GO-specific QOL scores with disease severity and activity. SUBJECTS AND METHODS Seventy three GO-specific QOL surveys were prospectively analysed and compared with GO status. The GO-specific QOL survey was trans...

Objective Infertility has an adverse effect on Quality of Life (QoL). The present study aimed to evaluate QoL and its effective factors in infertile couples. MaterialsAndMethods Fertility Quality of Life (FertiQoL) Instrument was used to measure QoL among 500 volunteer couplesattending the infertility clinic of Mother and Child Hospital in Shiraz, Iran. The participants’ demographic and clinica...

BACKGROUND Quality of life (QOL) is an important consideration for people living with advancing chronic conditions. Palliative care providers speak about how, despite physical decline in late life, many patients report growth and meaning in other domains. This mixed methods study uses QOL survey responses to explore domain trajectories and interview data to explore how patients with advancing c...

BACKGROUND With current treatments, approximately 75% of children diagnosed with cancer can expect to achieve disease-free survival. However, treatments are complex and aggressive, potentially compromising QOL for children and their parents. Although previous work has shown increased anxiety and depression among parents after diagnosis, the recent development of standardised measures of QOL ena...

PURPOSE To study the course of quality of life (QoL) after radiation therapy for painful bone metastases. PATIENTS AND METHODS The Dutch Bone Metastasis Study randomized 1157 patients with painful bone metastases between a single fraction of 8 Gy and 6 fractions of 4 Gy between 1996 and 1998. The study showed a comparable pain response of 74%. Patients filled out weekly questionnaires for 13 ...

BACKGROUND Quality of life (QoL) is increasingly measured in both research and clinical practice. QoL-assessments are built on a long, empirically-based, and stringent approach. There is ample evidence that QoL is, in part, heritable. We therefore performed a GWAS relating genetic variation to QoL in healthy females. METHODS In 5,142 healthy females, background characteristics (e.g. demograph...

Background: As world's population is growing, quality of life (QOL) and related factors such as self-care keep gaining mounting attention as they may affect the lives of the elderly significantly. The majority of the elderly people suffer from at least one chronic illness which plays an important role in elderly QOL. Objectives: This study was conducted to investigate self-care and related fac...

The aims of this retrospective analysis were (i) to examine the trends of quality of life (QoL) scores and (ii) to identify the risk factors for QoL scores among 6908 dialysis patients entering dialysis between 1997 and 2002. The Spitzer QoL Index was the instrument used by the National Renal Registry of Malaysia to assess the QoL amongst dialysis patients. Demographic and biochemical data were...

Quality of life (QoL) is increasingly becoming a key concept in research and clinical services. However, no agreement exists on what QoL is and how it is to be measured. This paper reviews three different yet linked approaches to QoL conceptualization: QoL as subjective well-being; QoL as achievement; and QoL as utility. People with spinal cord injury (SCI) tend to report fewer feelings of well...