نتایج جستجو برای: pyrazolones
تعداد نتایج: 119 فیلتر نتایج به سال:
Amyotrophic lateral sclerosis (ALS) is an orphan neurodegenerative disease currently without a cure. Mutations in copper/zinc superoxide dismutase 1 (SOD1) have been implicated in the pathophysiology of this disease. Using a high-throughput screening assay expressing mutant G93A SOD1, two bioactive chemical hit compounds (1 and 2), identified as arylsulfanyl pyrazolones, were identified. The st...
Synthesis, Evaluation and Docking Study of 1, 3, 5-Triazine Derivatives as Cytotoxic Agents against Lung CancerMarwa F. Balaha, Mervat H. El-Hamamsy, Nabawya A. Sharaf El-Din, Nageh A.El-Mahdy
An improved domino/Knoevenagel-hetero-Diels-Alder reaction of two new aldehyde substrates; 7-olefinoxy-coumarin-8-carbaldehyde and 2-alkensulfanyl-quinoline-3-carbaldehyde, with pyrazolones was studied in ionic liquid triethylammonium acetate (TEAA), affording a series of pyrazolopyran annulated-pyrano-fused coumarins, and thiopyrano-fused quinolones. Besides acting as catalyst, since no additi...
The preparation of Lanthanon octa-coordinated mixed chelates with different types of ligands is uncommon. Thompson and Loraas [1] have shown the presence of octacoordinated mixed chelates in solution. Recently, Dutt and Sur [2] have actually isolated several mixed tetrakis compounds of La, Pr, Nd, and Sm with three acetylacetone (Acac) molecules, the other ligands being propionylacetone or benz...
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