Pyoderma gangrenosum – a rare, neutrophilicdermatosis – is associated with diseases, including inflammatory bowel disease, arthritis and haematologic disease. It is a condition of unknown etiology. It is the result of an exaggerated response to specific and non-specific stimuli. First-line treatment is with a steroid, usually prednisone. Here we report a case of 60-year-old female presented to ...

An atypical pyoderma gangrenosum mimicking a post surgical cutaneous and subcutaneous infection is being reported for the first time in international literature after knee replacement surgery with the operation site being the starting point of pyoderma gangrenosum. Orthopedic surgeons and general surgeons should be aware of the existence of this disease and its association with surgical trauma.

<p>Pyoderma gangrenosum (PG) is an uncommon neutrophilic dermatosis characterized by painful skin ulcers. It associated with various systemic diseases but rarely orthopedic conditions. We report a case of pyogenic in 40-year-old male, that occurred association lower limb fracture. This patient suffered laceration over the ankle which was sutured initially and fracture managed conservative...

BACKGROUND Pyoderma gangrenosum is an aseptic skin disease. The ulcerative form of pyoderma gangrenosum is characterized by a rapidly progressing painful irregular and undermined bordered necrotic ulcer. The aetiology of pyoderma gangrenosum remains unclear. In about 70% of cases, it is associated with a systemic disorder, most often inflammatory bowel disease, haematological disease or arthrit...

pyoderma gangrenosum (pg) is a painful skin lesion that results from excessive inflammatory response to a host of traumatic, inflammatory, or neoplastic processes in susceptible individuals. a clear pathogenetic mechanism as well as an exhaustive list of potential triggers for pg is yet to be fully characterized. this case documents the occurrence of pyoderma gangrenosum following leech-therapy...

We report the rare occurrence of erythema nodosum and pyoderma gangrenosum at different times during the clinical course in a 30-year-old gentleman. He initially presented with biopsyproven erythema nodosum over both shins. He subsequently developed multiple violaceous and vegetative nodules over the upper and lower limbs. Three serial skin biopsies were performed thereafter. A diagnosis of veg...

DLBCL: diffuse large B-cell lymphoma PBL: plasmablastic lymphoma PG: pyoderma gangrenosum INTRODUCTION Pyoderma gangrenosum (PG) is an uncommon neutrophilic dermatosis characterized by the rapid development of painful, ill-defined ulcerations with undermined gun-metal gray borders. Although half of the cases are idiopathic, PG may be associated with inflammatory bowel disease, connective tissue...

We report 3 cases of breast pyoderma gangrenosum in patients undergoing total mastectomy with immediate reconstruction. All three received systemic corticosteroid treatment, resulting in resolution of symptoms. As experience grew, early diagnosis in the third patient helped prosthesis salvage and timely return to the original course of reconstruction. This represents the first report of prosthe...

Introduction PAPA syndrome (pyogenic arthritis, pyoderma gangrenosum and acne syndrome) is a rare autoinflammatory disease caused by mutations in the PSTPIP1 gene. This disease is difficult to treat, but the combination of prednisone, an IL-1 inhibitor and a TNF-inhibitor has, in our experience, helped even the most severely affected patients. Treatment with anakinra appears to prevent most of ...

BACKGROUND Atypical forms of pyoderma gangrenosum generally appear on the upper extremities; most frequently they are associated with myeloproliferative disorders, including osteomyelofibrosis. A response to systemic steroids is more pronounced than in classical form. Sometimes it may be the first sign of an underlying malignancy. CASE REPORT We reported a patient with atypical pyoderma gangr...