Trains of ultrarapid stimuli that begin late in the refractory period have been reported both to produce early single captures to terminate tachyarrhythmias and to inhibit the response to subsequent threshold stimuli. To determine which characteristics of trains facilitate capture and which enhance inhibition, we compared the right ventricular strength interval relationship for single extrastim...

In this research, optimization of the pulsed gas tungsten arc welding including pulse current, background current, pulse frequency and on time were investigated in welding of non-similar materials of austenitic stainless steel AISI 316L and nickel-base super alloy of Monel 400 by using ERNiCr3 filler metal. In order to obtain optimum conditions of welding the Taguchi method with the L9 array wa...

Thin compressive layers within a laminar ceramic arrest large cracks (surface and internal) and produce a threshold strength. This phenomenon increases the damage tolerance of ceramics and will allow engineers to design reliable ceramic components for structural applications. The stress intensity factor derived for a crack sandwiched between two compressive layers suggests that the threshold st...

We report on the experimental results of microand nanostructures fabricated on the surface of fused silica by a train of two femtosecond laser pulses, a tightly focused 266 nm (ultraviolet, UV) pulse followed by a loosely focused 800 nm (infrared, IR) pulse. By controlling the fluence of each pulse below the damage threshold, microand nanostructures are fabricated using the combined beams. The ...

In this study we aim to resolve the contributions of facilitation and refractoriness at very short pulse intervals. Measurements of the refractory properties of the electrically evoked compound action potential (ECAP) of the auditory nerve in cochlear implant (CI) users at inter pulse intervals below 300 μs are influenced by facilitation and recovery effects. ECAPs were recorded using masker pu...

BACKGROUND Despite advances in transplant surgery and general medicine, the number of patients awaiting transplant organs continues to grow, while the supply of organs does not. This work outlines a method of organ decellularization using non-thermal irreversible electroporation (N-TIRE) which, in combination with reseeding, may help supplement the supply of organs for transplant. METHODS In ...

Pulse-coupled threshold units serve as paradigmatic models for a wide range of complex systems. When the state variable of a unit crosses a threshold, the unit sends a pulse that is received by other units, thereby mediating the interactions. At the same time, the state variable of the sending unit is reset. Here we present and analyze a class of pulse-coupled oscillators where the reset may be...

BACKGROUND Biphasic pulses produced by most commercially available TMS machines have a cosine waveform, which makes it difficult to study the interaction between the two phases of stimulation. OBJECTIVE We used a controllable pulse TMS (cTMS) device delivering quasi-rectangular pulse outputs to investigate whether monophasic are more effective than biphasic pulses. METHODS Temporally symmet...

Divided-pulse amplification (DPA) has proven to be a valuable tool in scaling the peak power of diode-pumped ytterbium-doped amplifiers to beyond the single-pulse threshold for parasitic nonlinear effects. DPA enables the amplification of picosecond pulses in solid-state amplifiers with limited bandwidth beyond the single-pulse damage threshold. In this Letter, we demonstrate DPA of picosecond ...