PURPOSE Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airflow obstruction and pulmonary emphysema. Persistent inflammation and remodeling of the lungs and airways result in reduced lung function and a lower quality of life. Galectin (Gal)-9 plays a crucial role as an immune modulator in various diseases. However, its role in the pathogenesis of pulmonary emphysem...

OBJECTIVES The objective of this study was to determine whether automated quantification of lung perfused blood volume (PBV) in dual-energy computed tomographic pulmonary angiography (DE-CTPA) can be used to assess the severity and regional distribution of pulmonary hypoperfusion in emphysema. MATERIALS AND METHODS We retrospectively analyzed 40 consecutive patients (mean age, 67 [13] years) ...

Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammatory lung disease characterized by persistent airway inflammation. Spirometry considered gold standard for diagnosing COPD severity, high Resolution CT needed the analysis of various phenotypes and to quantify emphysema. Therefore, we conducted study assessment clinical severity using spirometry correlating it with High-Resolutio...

Gas within the wall of the stomach is a rare 350 Australasian Radiology. V o l . X X VIII, No. 4 , Novcjmber, I984 GASTRIC EMPHYSEMA: AN ETIOLOGIC CLASSIFICATION Clinical Signs and Symptoms None Severe vomiting with obstructive symptoms None related to gastric emphysema. Pulmonary symptoms present due to chronic obstructive pulmonary disease TY pes _ Etiology and Pathogenesis Distension of lume...

INTRODUCTION Pulmonary interstitial emphysema is a life-threatening form of ventilator-induced lung injury. We present one of the few reported adult cases of pulmonary interstitial emphysema in a woman with respiratory failure admitted to our intensive care unit. CASE PRESENTATION An 87-year-old Caucasian woman with a diagnosis of community-acquired pneumonia was admitted to our intensive car...

Editorial Chronic obstructive pulmonary disease (COPD) summarizes chronic bronchitis and lung emphysema. A major trigger for this disease is cigarette smoking. However, the occurrence and role of pulmonary vascular remodeling and pulmonary hypertension (PH) in COPD is not clarified yet. Although PH and lung vascular remodeling were thought to be infrequent events in COPD, recent clinical data e...

DOI: 10.1164/rccm.2107027 Internet address: www.atsjournals.org In 120 patients with severe emphysema evaluated for participation in the National Emphysema Treatment Trial, pulmonary hemodynamics and ventricular function were assessed. Pulmonary function tests were (%predicted): FEV 1 27%; residual volume 224.6%; diffusion capacity 26.7%. In 90.8% of patients, endexpiratory pulmonary artery mea...

Bronchoscopy with bronchoalveolar lavage (BAL) is an important research tool for assessing airway inflammation in a variety of inflammatory lung diseases. In chronic obstructive pulmonary disease (COPD), BAL recovery is often low, making analysis of the recovered fluid difficult to interpret. The present authors hypothesised that the degree of emphysema may predict BAL recovery. A total of 20 C...

In 2005, the combined pulmonary fibrosis and emphysema (CPFE) was first defined as a distinct entity, which comprised centrilobular or paraseptal emphysema in the upper pulmonary lobes, and fibrosis in the lower lobes accompanied by reduced diffused capacity of the lungs for carbon monoxide (DLCO). Recently, the fibrosis associated with the connective tissue disease was also included in the dia...