We previously demonstrated immune activation in the maternal peripheral circulation associated with preterm labor (PTL). There was an elevation in WBC mRNA of anti-inflammatory complement decay-accelerating factor (CD55) and the innate-immune response activating toll-like receptor 4 (TLR4). These findings suggested that collectively, these two molecules might serve as useful biomolecules to aid...

AIM To evaluate the feasibility and efficacy of percutaneous transhepatic lymphosonography (PTL) as a novel method for the detection of tumor lymphangiogenesis in hepatic VX(2) of rabbits and to evaluate combined PTL and routine contrast-enhanced ultrasonographic imaging for the diagnosis of liver cancer. METHODS Ten rabbits with VX(2) tumor were included in this study. SonoVue (0.1 mL/kg) wa...

BACKGROUND Interfering with cell proliferation and survival is a critical role for antineoplastic drugs leading to cell death through induction of apoptosis. Alternative treatments with herbal extracts offer insights into acute myeloid leukemia (AML) therapy. Parthenolide (PTL), an extract from feverfew, induces apoptosis in primary human leukemia stem cells (LSCs) and bulk leukemic cell popula...

background: preterm labor (ptl) is the main challenge in prenatal health care, leads to high rate of mortality and  increases cost of health services. to evaluate the preterm delivery (ptd)?related risk factors, we decided to measure nitrite oxide metabolites and cervical length (cl) as the diagnostic and predictive tools for ptd in women and response to tocolytic therapy.materials and methods:...

OBJECTIVE Although intra-amniotic(IA) infection is present in both preterm labor and intact membranes(PTL) and preterm premature rupture of membranes(preterm-PROM), it is more common in preterm-PROM than in PTL. Microorganisms and their products in the amniotic-cavity can elicit an inflammatory-response in fetus as well as in amniotic-cavity in the progression of acute histologic chorioamnionit...

Primary thyroid lymphomas (PTL) are extremely uncommon neoplasms accounting for 5% of all thyroid malignancies. There are very few small series and occasional case reports of fine needle aspiration cytology (FNAC) of PTL in literature. We present an interesting and rare case of PTL diagnosed on FNAC. FNAC is an important tool in the diagnosis of thyroid lymphoma. Journal of Cytology 2007; 24 (3...

background: patients with arrested preterm labor (ptl) are at increased risk for recurrence of preterm birth (ptb). maintenance tocolysis after arrest of acute ptl is of questionable value. the objective of this study was to evaluate the efficacy of 200 mg vaginal progesterone in order to prevent ptb in women with episodes of threatened ptl. materials and methods: this is a randomized double bl...

OBJECTIVES Pathological complete response and tumor regression to less than 10% vital tumor cells after induction chemoradiotherapy have been shown to be prognostically important in non-small cell lung cancer (NSCLC). Predictive imaging biomarkers could help treatment decision-making. The purpose of this study was to assess whether postinduction changes in tumor FDG uptake could predict patholo...

BACKGROUND Preterm birth is now recognized as the primary cause of infant mortality worldwide. Interplay between hormonal and inflammatory signaling in the uterus modulates the onset of contractions; however, the relative contribution of each remains unclear. In this study we aimed to characterize temporal transcriptome changes in the uterus preceding term labor and preterm labor (PTL) induced ...

Starting from the active ingredient shikimic acid (SA) of traditional Chinese medicine and NH2(CH2) n OH, (n = 2-6), we have synthesized a series of new water-soluble Pt(II) complexes PtL(a-e)Cl2, where L(a-e) are chelating diamine ligands with carbon chain covalently attached to SA (L(a-e) = SA-NH(CH2) n NHCH2CH2NH2; L(a), n = 2; L(b), n = 3; L(c), n = 4; L(d), n = 5; L(e), n = 6). The results...