Objectives-This project was conducted to examine whether the computerised analysis of psychomotor responses available from Cognitive Drug Research is appropriate for measuring an effect oflow level exposure to mercury in dentists. Methods-A computerised battery of psychomotor tests was given to two groups of dentists (older dentists and trainees) and to two age matched control groups. As well a...

Aim: To evaluate and compare the acute effects of citalopram and imipramine on psychomotor performance in healthy volunteers. Methods: 30 healthy male participants (20-35 yrs) received single oral doses of citalopram (20 mg), imipramine (50 mg) and placebo in a double blind, cross over study. A battery of objective (critical flicker fusion, digit letter substitution, six letter cancellation, ar...

The Finnish clinical test for drunkenness is a medicolegal test developed to detect alcoholinduced impairment of driving fitness. This test comprises motor, vestibular, mental and behavioral subtests. The ability of the clinical test for drunkenness to reveal drug-effects on performance was compared with that of selected psychomotor laboratory tests. Psychomotor laboratory tests included simula...

The increasing incidence of cardiovascular disease and subsequent depressive symptoms has highlighted the potential for concomitant treatment of β-blockers and antidepressant medication. It has been noted that both types of medications are associated with decrements in psychomotor and cognitive performance. Thus, the aims of this study were to characterise the psychomotor performance characteri...

Introduction: Psychomotor performance task is used to assess the arousal and cognitive functions of the central nervous system. Alternatively, human visual working memory reflects the capability of the individual’s short-term memory. Psycho-mental stimuli are linked to the stimulation of Malondialdehyde (MDA) formations. Citicoline is a nootropic nucleotide agent with a favorable effect on the ...

Δ9-Tetrahydrocannabinol (THC), the primary psychoactive constituent in cannabis, impairs psychomotor performance, cognition and driving ability; thus, driving under the influence of cannabis is a public safety concern. We documented cannabis' psychomotor, neurocognitive, subjective and physiological effects in occasional and frequent smokers to investigate potential differences between these sm...

BACKGROUND AND AIMS Melatonin (MT), a naturally occurring pituitary hormone has a sleep promoting effect. There are very few studies on pre-operative oral MT (0.2-0.5 mg/kg) in children. We planned a study to assess the efficacy of oral MT in two doses and compare it with oral midazolam and placebo for pre-operative anxiolysis, sedation, maintenance of cognition and psychomotor skills, parental...

Behavioural changes are produced by any drug that enters the central nervous system. These psychoactive effects include changes in alertness, concentration, attention, memory, cognition, psychomotor accuracy, skilled performance and affect. Changes in psychological performance may affect the safety of both the individuals taking the drug and of those people coming into contact with them. The ai...

OBJECTIVE To examine whether aerobic fitness moderated age differences in within-person reaction time variability (WP RT variability) and given conceptual linkage involving the frontal cortex, whether effects were mediated by executive function. METHOD Aerobic fitness (estimated VO2max) and WP RT variability were investigated in 225 healthy, community-dwelling adults aged 50-90 years (M = 63....

The stimulatory effects of acute caffeine intake on choice reaction time, mood state, and visual vigilance are well established. Little research exists, however, on the effects of chronic caffeine ingestion on psychomotor tasks. Therefore, the purpose of this study was to evaluate the effects of 5 days of controlled caffeine intake on cognitive and psychomotor performance. Three groups of 20 he...