Increase in biological data at an alarming rate, has made possible the use of such data in identification of drug targets. Ureaplasma urealyticum serovar 10 str. ATCC 33699 is a causative agent for sexually transmitted infections. In present study novel comparative genomic approach is used to identify the drug targets. This approach has been successfully used in Pseudomonas aeroginosa. In curre...

Methanolic extract of Hairs and Glands covering fruits of Mallotus philippinensis (kamala powder) were subjected to Antimicrobial and toxicological screening. Antimicrobial profile indicated that extract was effective against all Gram positive cocci and bacilli used in the study. Among Gram negative bacilli, three important pathogenic species i.e. Salmonella typhi, Salmonella para typhiA and Ps...

Lactoferrin (Lf) is an 80 kDa iron-binding glycoprotein with multifunctional properties and useful for clinical and commercial applications. Currently, Lf has some advantages including, immune system modulation, antibacterial activity and as antioxidant in infant and adult of human as well as animal health. In the present study, antibacterial activity of Lf has been scrutinized after isolation ...

The antimicrobial activity of plant extracts were found in folk medicine as essential oils or isolated compounds. Some of these compounds were isolated or obtained by bio-guided isolation after previously detecting antimicrobial activity on the part of the plant. Petunia is an imporant medicinal and ornamental plant.The in vitro callus induction and antibacterial activity of Petunia leaf and ca...

The ligand, N,N'-bis(salicylidine)ethylenediamine or salen (L), and its complexes 1-3 with Ni(II), Cu(II) Mn(II) were synthesized. Various analytical methods such as microanalysis, 1H-NMR, 13C-NMR, ESI-MS FT-IR spectroscopy has been used to characterize the synthesized compounds. Antibacterial activity of prepared compounds tested against two Gram-positive bacteria Staphylococcus aureus Bacillu...

Nigella sativa seeds (blackseed; kalonji) have been used in traditional medicine for the treatment of a variety of diseases including diarrhea and asthma. In this study, the antibacterial and antifungal effects of the aqueous, methanol and chloroform extracts of the seeds against standard and hospital strains of Candida albicans, coagulase-positive Staphylococcus aureus (CPSA) and Pseudomonas a...

background: ventilator-associated pneumonia (vap) is a type of nosocomial pneumonia which develops more than 48 hours after endotracheal intubation. early recognition and treatment of vap is important, since timely and appropriate management can be lifesaving. objectives: this study aimed to determine the antimicrobial susceptibility pattern of microorganisms causing vap in the intensive care u...

This paper presents some results concerning the immobilization through chemical bonds of some biologically active compounds on the maleic anhydridemethyl methacrylate) copolymer. The high reactivity of the anhydride cycle of the polymer has allowed us to obtain conjugates in which the biologically active compounds of some heterocyclic compounds are immobilized on the polymeric support through a...