In this work a novel bioassay for mustard agent detection was proposed. The bioassay is based on the capability of these compounds to inhibit the enzyme choline oxidase. The enzymatic activity, which is correlated to the mustard agents, was electrochemically monitored measuring the enzymatic product, hydrogen peroxide, by means of a screen-printed electrode modified with Prussian Blue nanoparti...

BACKGROUND Superparamagnetic nanoparticles are currently used as contrast agents for magnetic resonance imaging. These particles can also be used as drug carriers for local chemotherapy, called magnetic drug targeting. Using an external magnetic field, colloidal nanoparticles can be directed to a specific body compartment (i.e. tumor). MATERIALS AND METHODS After magnetic drug targeting in an...

As far as is known, the pigment Prussian blue was synthesised for the first time in Berlin in the early 1700s. It is commonly assumed that the pigment was not used in paintings before the 1720s. The presence or absence of this pigment is often used to answer questions concerning the dating and authenticity of art objects from the 18th Century. For the very first time, a large collection of Fren...

Prussian Blue (ferric hexacyanoferrate(II)) was discovered accidentally by Johann Jacob Diesbach (1) and Johann Konrad Dippel (2) in Berlin in 1706 (3). As the first synthetic pigment, Prussian Blue received its name from the country in which its discovery occurred. It revolutionized the use of the color blue in artwork because it was less expensive and/or more stable than other blue pigments o...

Developing methods that evaluate the cellular uptake of magnetic nanoparticles (MNPs) and nanotoxicity effects at single-cellular level are needed. In this study, magnetophoresis combining fluorescence based cytotoxicity assay was proposed to assess the viability and the single-cellular MNPs uptake simultaneously. Malignant cells (SKHep-1, HepG2, HeLa) were incubated with 10 nm anionic iron oxi...

Prussian blue is an ancient artificial pigment. Its biocompatibility and the possibility of synthesizing it in nanometric size stimulated interest scientific community. Many uses nanoparticles have been reported field nanomedicine. More recently, into potential application as antibacterial agents has spread. Literature regarding its analogs materials still limited, but number papers grown quick...