background: to develop a new green approach for biosynthesis of silver nanoparticles, myconanotechnology has been represented as a novel field of study in nanotechnology. in this study, we have reported the extracellular synthesis of highly stable silver nanoparticles using three species of dermatophytes: trichophyton rubrum, trichophyton mentagrophytes and microsporum canis. methods: clinical ...

Background: Stearoyl-CoA desaturase (SCD) is a key enzyme that converts saturated fatty acids (SFAs) to monounsaturated fatty acids (MUFAs) in fat biosynthesis. Despite being crucial for interpreting SCDs’ roles across species, the evolutionary relationship of SCD proteins across species has yet to be elucidated. This study aims to present this evolutionary relationship based on amino aci...

Antimycins are anticancer compounds produced by a hybrid nonribosomal peptide synthetase/polyketide synthase (NRPS/PKS) pathway. The biosynthesis of these is well characterized, with the exception standalone ?-ketoreductase enzyme AntM that proposed to catalyze reduction C8 carbonyl antimycin scaffold. Inactivation antM and structural characterization suggested rather than functioning as post-P...

Drought is a major limiting factor of Brassica napus (rapeseed) and potassium (K) plays important roles in rapeseed drought tolerance. Previous studies have reported that cultivars characterized by different K status showed contrasting However, the molecular mechanism underlying tolerance remains unclear. In this study, comparative transcriptome analysis was conducted between drought-tolerant c...

Rice blast, caused by Magnaporthe oryzae is one of the most destructive diseases rice ( Oryza sativa L.) in rice-cultivated areas worldwide. Mowanggu (MWG) a traditional landrace variety Yunnan with broad-spectrum and durable blast resistance against fungus. However, underlying disease-resistance mechanisms remain unknown. An integrative transcriptomic, proteomic, phosphoproteomic analysis MWG ...

Survival of plants and nearly all organisms depends on the pterin based molybdenum cofactor (Moco) as well as its effective biosynthesis and insertion into apo-enzymes. To this end, both the central Moco biosynthesis enzymes are characterized and the conserved four-step reaction pathway for Moco biosynthesis is well-understood. However, protection mechanisms to prevent degradation during biosyn...

The present study aimed to investigate whether skeletal muscle from whole body creatine transporter (CrT; SLC6A8) knockout mice (CrT(-/y)) actually contained creatine (Cr) and if so, whether this Cr could result from an up regulation of muscle Cr biosynthesis. Gastrocnemius muscle from CrT(-/y) and wild type (CrT(+/y)) mice were analyzed for ATP, Cr, Cr phosphate (CrP), and total Cr (TCr) conte...

Abstract The DWARF AND LOW TILLERRING ( DLT ) gene is a transcription factor for involved in Brassinosteroid (BR) biosynthesis. Manipulating BR biosynthesis will affect the height and tiller number of rice. CRISPR-Cas9 an accurate tool to edit sequence. accuracy site editing CRISPR-Cas9-mediated target determined by 20 nucleotide sequences sgRNA binding known as Protospacer Adjacent Motif (PAM)...