Multidrug resistance (MDR) is a complex phenomenon in which many different genes regulating drug transport, cellular repair, detoxification and drug metabolism are involved. Nevertheless, in most drug resistant cell lines and cancer patients up-regulation of ABC-transporter genes such as MDR associated Protein (MRP1) gene could be at the basis of the drug resistance phenotype. We aimed to decre...

introduction : designing an effective vaccine against human immunodeficiency virus (hiv)-1 is a global health priority . multi-epitope vaccines offer several potential advantages that may be promising in case of mutable divergent pathogens such as hiv-1. herein, a multiepitopic recombinant protein containing various hiv-1 antigens was expressed in e. coli cells and its immunogenicity in combina...

background : there is disagreement on the effect of diabetes on oral hygiene. the purpose of this study was to assess the oral health and hygiene status of type 1 diabetic patient. methods : in this case control study, periodontal health and hygiene of 80 children and adolescents (5–18 yr of age) with type 1 diabetes mellitus referred to pediatric endocrine clinic of besat hospital hamadan iran...

the reflectance spectrum of green leaves is considerably affected by their biochemical and biophysical properties. it is possible to extract biochemical information from a continuous vegetation spectrum produced using hyperspectral sensors. the numerous absorption features present in the vegetation spectrum carry a considerable amount of information related to the content and the structure of t...