نتایج جستجو برای: prostate carcinoma

تعداد نتایج: 479170  

Journal: :The Journal of the American Board of Family Practice 2003
Christopher Trotz

Pure small cell carcinoma of the prostate is extremely rare. When it does occur, it is usually in concordance with prostatic adenocarcinoma. Early diagnosis is difficult as the carcinoma tends to spread early to visceral organs without concordant elevation of prostate-specific antigen (PSA). Because this condition is rare, no standard treatment regimen has been established, and the overall prog...

Journal: :Cancer research 2002
Igor Kuzmin John W Gillespie Alexei Protopopov Laura Geil Koen Dreijerink Youfeng Yang Cathy D Vocke Fuh-Mei Duh Eugene Zabarovsky John D Minna Johng S Rhim Michael R Emmert-Buck W Marston Linehan Michael I Lerman

We analyzed expression status of the recently identified tumor suppressor geneRASSF1A in primary prostate carcinomas and in prostate cell lines. We found complete methylation of the RASSF1A promoter in 63% of primary microdissected prostate carcinomas (7 of 11 samples). The remaining 4 samples (37%) were partially methylated, possibly because of contamination with normal cells. No promoter meth...

2017
Amarnath Jena Shuaib Zaidi Vikas Kashyap Abhishek Jha Sangeeta Taneja

PSMA PET is increasingly being used in imaging of recurrent prostate carcinoma. A case with suspected recurrent Prostate carcinoma (PCa), raised PSA (Prostate specific antigen) and suspected spinal metastases was referred for whole body Ga-68-PSMA PET/MRI. The study revealed PSMA avid recurrent prostate mass and extensive osseous metastases. Abnormal PSMA uptake in the thyroid gland prompted US...

2014
KEIKO YOSHIDA MITSUAKI ISHIDA AKIKO KAGOTANI NOZOMI IWAMOTO MUNEO IWAI HIDETOSHI OKABE

The occurrence of small cell carcinoma in the urinary bladder and prostate is rare. Only a few reports on the cytological features of small cell carcinoma of the urinary bladder in the urine specimen have been documented and, moreover, the urinary cytological features of prostate small cell carcinoma have been rarely reported. In this study, we analyzed the cytological features of four cases of...

Journal: :The Prostate 2003
Nigel Clegg Camari Ferguson Lawrence D True Hugh Arnold Alec Moorman Janna E Quinn Robert L Vessella Peter S Nelson

OBJECTIVES A subset of prostate carcinomas is composed predominantly, even exclusively, of neuroendocrine (NE) cells. In this report, we sought to characterize the gene expression profile of a prostate small cell NE carcinoma by assessing the diversity and abundance of transcripts in the LuCaP 49 prostate small cell carcinoma xenograft. METHODS We constructed a cDNA library (PRCA3) from the L...

2017
Xiao-Nan Mu Si-Jun Wang Zhi-Gang Sun Min Zhang Zhe Li Long-Yang Zhang

Adenocarcinoma of prostate with mucinous differentiation arising in the male urethra is extremely rare, with only 21 cases reported in the previous literature. A diagnosis of mucin-producing urothelial carcinoma of the prostate is based on the pathology, immunohistochemistry, and clinical examination by excluding the secondary adenocarcinoma of the prostate. We present a case of unexpected muci...

2014
Kursat Cecen Mert Ali Karadag Aslan Demir Ramazan Kocaaslan

INTRODUCTION Small cell carcinoma of the prostate is a very rare and aggressive type of prostatic cancer. Most cases are diagnosed at advanced stage due to early metastasis. The bones, liver, regional and distant lymph nodes are the most common sites of metastasis of small cell carcinoma of the prostate. Skin metastasis of small cell carcinoma of the prostate is a very rare entity due to the un...

Journal: :Cancer 2004
Jennifer L Beebe-Dimmer David P Wood Stephen B Gruber Doug M Chilson Kimberly A Zuhlke Gina B Claeys Kathleen A Cooney

BACKGROUND It is important for clinicians, researchers, and others who shape public health policy to understand the demographic correlates and psychologic factors that drive health behaviors, such as screening for early detection of cancer, particularly among individuals at high risk for developing the disease. METHODS One-hundred eleven men whose brothers were diagnosed with prostate carcino...

Journal: :International journal of advanced research 2021

As number of cancer patients increasing, the chemotherapy treatments are also increasing. This analysis aims to provide a cutting-edge outline antineoplastic medications extracted from streptomyces. Streptomyces main source antibiotic production. Antineoplastic moderate pace tumor development and postpone metastasis. The utilization performance methods discussed, with focus on drugs. produces c...

Journal: :The Prostate 2009
Donna E Hansel Masashi Nakayama Jun Luo Abde M Abukhdeir Ben H Park Charles J Bieberich Jessica L Hicks Mario Eisenberger William G Nelson Jasek L Mostwin Angelo M De Marzo

BACKGROUND Small cell carcinoma of the prostate is an uncommon neoplasm, the origin of which has been controversial. To address this, we performed transcriptome profiling and TP53 sequencing of concurrent small cell and prostatic adenocarcinoma to determine the relationship between these entities. METHODS We identified an unusual case of primary prostate cancer that contained adjacent acinar ...

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