Coccydynia is a common condition that has been difficult to treat effectively with conventional pain relief methods. There has been previous research demonstrating safety and efficacy of prolotherapy to treat coccydynia. Many of the original descriptions were performed utilizing landmark or palpation guided techniques. However, there is evidence that imaging guidance improves accuracy of inject...

Osteoarthritis is a chronic, progressive disease of the articular joints, and to date, has no cure or effective longterm treatment. Objective: To determine if bone marrow prolotherapy (BMP), a combined treatment protocol employing separate injections of hypertonic dextrose prolotherapy and bone marrow aspirate, would be effective as a means of reducing joint pain and improving function in osteo...

OBJECTIVES To assess the efficacy of a prolotherapy injection and exercise protocol in the treatment of chronic nonspecific low back pain. DESIGN Randomized controlled trial with two-by-two factorial design, triple-blinded for injection status, and single-blinded for exercise status. SETTING General practice. PARTICIPANTS One hundred ten participants with nonspecific low-back pain of aver...

Background: Carpal tunnel syndrome (CTS) is a common neuropathy condition caused by entrapment of the median nerve. Perineural injection therapy with 5% dextrose or prolotherapy becoming method for treating carpal syndrome. Although it effective, some anatomical variaton nerve could effect outcome in CTS. Case Report: A 43-year-old woman suffered from diurnal, nocturnal numbness and paraesthesi...

Background: Platelet-Rich Plasma (PRP) has been used for a variety of musculoskeletal disorders including tendinopathies and Osteoarthritis. Few studies exist for PRP in the spine, except for studies involving disc pathology. However, numerous studies exist involving the use of Prolotherapy for spinal disorders. Both Prolotherapy and PRP can be considered within the broad category of Regenerati...

Background Regenerative injection therapies such as prolotherapy have gained importance in the recent years non-surgical management of supraspinatus tendinopathy. The aim present study was to compare efficacy isometric rotator cuff strengthening versus corrective exercise program treatment Material and Methods Fifty patients aged 18 - 60 were recruited with MRI diagnosed isolated tendinopathy o...