BACKGROUND The cardiovascular complications of cancer therapeutics are the focus of the burgeoning field of cardio-oncology. A common challenge in this field is the impact of cancer drugs on cardiac repolarization (ie, QT prolongation) and the potential risk for the life-threatening arrhythmia torsades de pointes. Although QT prolongation is not a perfect marker of arrhythmia risk, this has bec...

The correct measurement of the QT interval (using correction formulas, preferably Fridericia and Framingham) as well a interpretation causes clinical consequences prolongation is very important in practice. Drug-induced long syndrome (DILQTS) one most common LQTS. In diagnosis management DILQTS, it can be useful to follow three-step rule presented this article: detailed pharmacological anamnesi...

BACKGROUND QRS prolongation is associated with adverse outcomes in mostly white populations, but its clinical significance is not well established for other groups. We investigated the association between QRS duration and mortality in African Americans. METHODS AND RESULTS We analyzed data from 5146 African Americans in the Jackson Heart Study stratified by QRS duration on baseline 12-lead EC...

Introduction Temporary QT-interval prolongation following intracranial hemorrhage and hydrocephalus has been repeatedly reported in adults. Case We report a case of excessive QT prolongation with sudden bradycardia resulting in 2:1 atrioventricular conduction in a preterm infant most likely associated with a congenital hydrocephalus. Pathomechanisms are discussed. Conclusion Congenital hydrocep...