In this paper, a boosting-based incremental hybrid intrusion detection system is introduced. This system combines incremental misuse detection and incremental anomaly detection. We use boosting ensemble of weak classifiers to implement misuse intrusion detection system. It can identify new classes types of intrusions that do not exist in the training dataset for incremental misuse detection. As...

Several recent nonrelativizing results in the area of interactive proofs have caused many people to review the importance of relativization. In this paper we take a look at how complexity theorists use and misuse oracle results. We pay special attention to the new interactive proof systems and program checking results and try to understand why they do not relativize. We give some new results th...

This article examines the biosecurity and biodefense implications resulting from the recent creation of horsepox virus, a noncirculating (extinct) species of orthopoxvirus. Here we examine the technical aspects of the horsepox virus synthesis and conclude that orthopox synthesis experiments currently remain technically challenging-and will continue to be so, even once this work is published in ...

BACKGROUND Alcohol-related injuries, particularly motor vehicle, are an important cause of adolescent mortality. School-based alcohol prevention programs have not been evaluated in terms of driving outcomes. This study examined the effects on subsequent driving of a high school-based alcohol prevention program. METHODS The Alcohol Misuse Prevention Study included a randomized test of the effe...

BACKGROUND Despite increased attention to dentists' roles in curbing opioid misuse, abuse, and diversion, information regarding prescribing practices and the frequency of multiple concurrent opioid prescriptions among dental patients is limited. METHODS The authors reviewed South Carolina prescription drug monitoring program data representing dispensed medication for patients prescribed at le...

BACKGROUND Prescription opioid misuse has doubled over the past 10 years and is now a public health epidemic. Analysis of social media data may provide additional insights into opioid misuse to supplement the traditional approaches of data collection (eg, self-report on surveys). OBJECTIVE The aim of this study was to characterize representations of codeine misuse through analysis of public p...