نتایج جستجو برای: prognostication prediction
تعداد نتایج: 255666 فیلتر نتایج به سال:
Introduction: Multiple myeloma is a heterogeneous disease with different survival times among patients. Accurate prediction of prognosis in multiple myeloma is essential, as patients with a shorter survival time may require early bone marrow transplantation (BMT) and more advanced chemotherapy as a part of their first-line treatment. In the present study, a parameter, depicted by ga...
ATR-CHEK1 signalling is critical for genomic stability. ATR-CHEK1 signalling may be deregulated in breast cancer and have prognostic, predictive and therapeutic significance. We investigated ATR, CHEK1 and phosphorylated CHEK1 (Ser345) protein (pCHEK1) levels in 1712 breast cancers. ATR and CHEK1 mRNA expression was evaluated in 1950 breast cancers. Pre-clinically, biological consequences of AT...
The care of the comatose cardiac arrest patient and his/her relatives in the ICU constitutes a major challenge for intensivists. Out-of-hospital cardiac arrest (OHCA) affects more than 275.000 Europeans yearly; survival rates are disturbingly low and have until recently remained unchanged [1]. During the last several years, significant efforts have been made to improve the quality of prehospita...
Richa Agarwal, MD Allegheny General Hospital Division of Cardiovascular Diseases, Section of Advanced Heart Failure, Transplantation, Mechanical Circulatory Support, and Pulmonary Hypertension Pittsburgh, PA Significant therapeutic advances in the field of pulmonary arterial hypertension (PAH), increased awareness and diagnosis, and changing patient demographics in the contemporary era have fac...
OBJECTIVE Patients with intracerebral haemorrhage (ICH) are at high risk of neurological deterioration (ND). We aimed at establishing predictors of early ND (END) as well as late ND (LND) and at exploring the impact of neurological stability during the first week on long-term prognosis. DESIGN We conducted this study as a retrospective cohort study. ND was evaluated based on the consciousness...
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