determining production rate considering costs and revenues in order to maximize profit is one of the applied problems in small and medium size factories. mostly existing models in production planning consider production system statically and specify production rate, although the factors determining production rate include many different changes in practice. in fact, by increasing the production...

E BULK OF DATA initially accumulated regarding the lymphocyte tended to indicate that its life span was relatively short. Thus, Minot and Isaacs,’ in 1925, transfused blood from a patient with chronic lymphocytic leukemia into a patient with lymphosarcoma. The recipient’s blood showed an elevated lymphocyte count for 35 minutes before returning to normal. Yoffey,2 in 1935, showed that in the do...

The bottleneck in a production-inventory network is commonly taken to be the facility that most limits flow through the network and thus the most highly utilized facility. A further connotation of “bottleneck,” however, is the facility that most constrains system-wide performance or the facility at which additional resources would have the greatest impact. Adopting this broader sense of the ter...

The entropy production rate was determined for avascular tumor growth. The proposed formula relates the fractal dimension of the tumor contour with the quotient between mitosis and apoptosis rate, which can be used to characterize the degree of proliferation of tumor cells. The entropy production rate was determined for fourteen tumor cell lines as a physical function of cancer robustness. The ...