Background. Amyloidosis is a group of disorders characterized by deposition of an extracellular protein, known as amyloid, in an abnormal fibrillar form with highly characteristic histopathologic staining properties. The clinical presentation can vary from a focal, localized lesion where amyloidosis has minor clinical consequences to extensive systemic disease that can involve any organ system ...

Primary systemic amyloidosis (AL) is an uncommon disease characterized by the extracellular deposition of a protein with a beta-fibrillar structure, consisting of monoclonal immunoglobulin light chains, lambda or kappa (ratio of lambda to kappa, 3:1). In systemic amyloidosis liver involvement is frequent but it rarely has clinical importance. The massive and localized liver deposition of amyloi...

AMYLOIDOSIS is usually categorized as a degenerative process. Nevertheless, the nature and pathogenesis of this disorder remain most uncertain. Reimann, Koucky, and Eklund (1935) have classified amyloidosis in four groups: primary, secondary, tumour-forming, and associated with multiple myeloma. Tumour-forming amyloidosis is known to occur as a primary process in the tissues of the eye, urinary...