The International Union of Immunological Societies now recognizes over 430 single gene inborn errors immunity, making the investigation suspected immunodeficiency in children increasingly complex. use immunomodulatory therapies, including biologics, may also cause both transient and permanent secondary immunodeficiency. This review outlines a practical approach to guide paediatric doctors allie...

  Primary non-Hodgkin lymphoma of liver is a very rare malignancy. Here we report a case of primary hepatic Burkitt’s lymphoma in a 34-year old man who was known case of acquired immunodeficiency syndrome (AIDS) and presented with weight loss, abdominal pain, and fever. Positive laboratory findings were mild anemia and elevated levels of lactate dehydrogenase (LDH) and alkaline phosphatase (AL...