A 42-year-old woman had pain in her hands and discoloration on the tips of her fingers and toes when exposed to cold (Figure 1). She had chronic systemic lupus erythematosus that was diagnosed seven years earlier. Her urinalysis findings were abnormal, including the presence of proteinuria and hematuria. Her creatinine level was normal, and her antinuclear antibody titer was 1:2,560. Renal biop...

Introduction Doxycycline is an antibiotic belonging to the group of tetracyclines. It is active against gram positive and gram negative bacteria. It has been on the Dutch market at least since 1973 and the oral preparation is indicated for infections of the respiratory tract, infections of the urogenital tract, infections of the skin and soft tissues, Borrelia burgdorfori infections, infections...

introduction: discoloration of dental composite resins is one of the most common reasons for replacement of these restorations. this in vitro study was carried out to evaluate the effect of aging on discoloration of silorane-based filtek p90 and micro-hybrid z250 composite resins. materials and methods:   this experimental study was carried out on 10 disk-shaped filtek p90 and z250 samples, mea...

The aim of this study was to assess the possibility of digital image analysis of pit-and-fissure discoloration in order to diagnose caries. Digital images showing pit-and-fissure discoloration in 100 teeth of 19 patients were analyzed to obtain the fractal dimension (FD) and the proportion of the area of pit-and-fissure discoloration to the area of occlusal surface (PA). DIAGNOdent values were ...